On the background of mobile, ubiquitous, and pervasive applications, context determination and assignment is a necessary factor to provide IT solutions suited to a user and the user’s current situation. In this paper, context is seen as n-ary relationship. Context gets embedded into ontologies, which are used to structure application specific knowledge. We present an integrative, case-based mod...

This paper considers a new kind of knowledge discovery among spatial objects|namely that of partial boundary shape matching. Our focus is on mining spatial data, whereby many objects called features (represented as polygons) are compared with one or more point sets called clusters. The research described has practical application in such domains as Geographic Information Systems, in which a clu...

Governmental and environmental agencies have recognized that Data Warehouses (DWs) oriented to environmental domain can cause a deep impact in the ability to preserve the environment. However, extracting environmental data from external sources in order to load them into the data organization area of a DW is much more complex when compared with conventional DWs. In environmental DWs, extraction...

In our Select pages, we highlight exciting themes that have emerged from our review of the recent literature on a particular topic. In this issue, we present Neurobiology Select in which we discuss a cluster of recent papers that increases our understanding of complex human neurological disorders such as schizophrenia, Tourette’s syndrome, and developmental dyslexia. Some of the genes implicate...

This paper presents a new approach for memory-based collaborative filtering algorithms. In general, user-based rating prediction is a process in which each neighbor suggests a rating for the target item and the suggestions are combined by weighting the contribution of each neighbor. We present a new alternative that is independent of user rating scales and is based on what we call predictive pr...

The ATR (ATM (ataxia telangiectasia mutated) and rad3-related) checkpoint kinase is considered critical for signalling DNA replication stress and its dysfunction can lead to the neurodevelopmental disorder, ATR-Seckel syndrome. To understand how ATR functions during neurogenesis, we conditionally deleted Atr broadly throughout the murine nervous system, or in a restricted manner in the dorsal t...

Many genetic and acquired liver disorders are amenable to gene and/or cell therapy. However, the efficiencies of cell engraftment and stable genetic modification are low and often subtherapeutic. In particular, targeted gene modifications from homologous recombination are rare events. These obstacles could be overcome if hepatocytes that have undergone genetic modification were to be selectivel...

In this paper we compare the performance of three distinct approaches to lexical cohesion based text segmentation. Most work in this area has focused on the discovery of textual units that discuss subtopic structure within documents. In contrast our segmentation task requires the discovery of topical units of text i.e. distinct news stories from broadcast news programmes. Our approach to news s...