Nevus sebaceous is a congenital, benign hamartomatous lesion, characterized by a yellowish to skin-colored, hairless, verrucous plaque on the head and neck region. In later life, a secondary tumor, either benign or malignant, can develop within nevus sebaceous. Eccrine poroma developing on nevus sebaceous is extremely rare. There are few case reports of eccrine poroma developing within nevus se...

Cystic sebaceous neoplasms have been seen only in patients with Muir-Torre syndrome (MTS) and have recently been characterized as marker lesions of MTS. Histologically, these lesions form a spectrum of tumors ranging from benign cystic adenomas to proliferative cystic sebaceous tumors. We describe 2 proliferative cystic sebaceous tumors in a 53-year-old man whose workup revealed colonic adenoca...

Sebaceous adenoma is rare lesion and frequently misdiagnosed clinically as basal cell carcinoma or squamous cell carcinoma. Sebaceous carcinoma are still rarer lesions taking origin from sebaceous glands.We report a case of sebaceous carcinoma on upper eyelid which was a diagnostic dilemma.Biopsy in this case was sent to us with clinical diagnosis of squamous cell carcinoma/Meibomian gland carc...

This paper reports a rare case of sebaceous adenoma on the right mandibular retromolar mucosa in a 73-year-old Japanese man, with a review of the English literature of sebaceous adenomas of salivary gland origin. A painless and yellowish polypoid lesion in the retromolar mucosa was histologically a relatively well-circumscribed neoplastic mass composed of well-differentiated sebaceous cells wit...

Sebaceous neoplasia comprises a spectrum ranging from benign to malignant. Proper histological identification is important for treatment, prognosis and potential association with the Muir-Torre syndrome (MTS). Our increased understanding of the significance and pathogenesis of these tumours has led to improved risk stratification, screening recommendations, and treatment of patients with an ini...

to be associatedwith HPV 16. Higher-weight cytokeratins are encountered in the epidermis as opposed to mucous membranes.2,3 The 2 major differential diagnoses were sebaceous and mucoepidermoid carcinomas.4 Sebaceous carcinomawasexcludedbyoil redOcytoplasmicnegativityand immunohistochemical stains that demonstrated negativity for both adipophilin (except for faint focal positivity in necrotic zo...

Sebaceous carcinoma is a very rare and potentially aggressive carcinoma originating from the epithelial lining of the sebaceous gland. More than 70% of all cases are in the head and neck region, especially the periorbita; therefore, they are classified into ocular and extraocular sebaceous carcinoma. The reported risk factors are advanced age, male sex, previous irradiation, and genetic predisp...

Cells from the mouse preputial gland tumor ESR 586 have been cultured and cloned. Trypsin-ethylenediaminetetraacetate was used to obtain single cells. The cells are grown in a modified CMRL-1415 medium supplemented with 10% fetal calf serum. Clones tend to fall into two classes: Class 1, those that undergo morphological differentiation in liquid medium to form round bodies filled with lipid vac...

Apocrine skin carcinoma is an aggressive cutaneous tumour. We report a case of apocrine carcinoma developing in a naevus sebaceous of scalp in a 45 years old male. Malignant transformation of Naevus sebaceous is a rare complication usually found in elderly patients. Most of these tumours are basal cell carcinoma or squamous cell carcinoma. Only few cases of apocrine carcinoma on naevus sebaceou...

Nowadays, most cosmetical and dermatological laboratories use sebocyte cell lines to study physiopathological conditions such as seborrhoea or acne. Immortalized human sebaceous gland provide large amounts of sebocytes but are not relevant primary that remain a better more useful tool for studying the activity regulation glands. However, part holocrine gland, once in culture, tend quickly stop ...