The historical foundations of cancer risk assessment were based on the discovery of X-ray-induced gene mutations by Hermann J. Muller, its transformation into the linear nonthreshold (LNT) single-hit theory, the recommendation of the model by the US National Academy of Sciences, Biological Effects of Atomic Radiation I, Genetics Panel in 1956, and subsequent widespread adoption by regulatory ag...

We appreciate the opportunity to comment on the Office of the Inspector General’s Sodium Iodide Symporter cumulative risk assessment which included perchlorate. We have attached our scientific comments on this cumulative risk assessment. We have responded to your request for comments in the following document titled Response to the Environmental Protection Agency Office of Inspector General Sci...

There is growing evidence that the spatial and temporal incidence of harmful algal blooms is increasing, posing potential risks to human health and ecosystem sustainability. Currently there are no US Federal guidelines, Water Quality Criteria and Standards, or regulations concerning the management of harmful algal blooms. Algal blooms in freshwater are predominantly cyanobacteria, some of which...

BACKGROUND Health technology assessment (HTA) is mostly used in the context of high- and middle-income countries. Many "resource-poor" settings, which have the greatest need for critical assessment of health technology, have a limited basis for making evidence-based choices. This can lead to inappropriate use of technologies, a problem that could be addressed by HTA that enables the efficient u...

today, journals are trying to improve their rankings both at local and international scales. achievement of the journal relies heavily on our ability to publish articles in scientific journals with the highest quality. in this regard, high quality manuscript review plays an important role in supporting editors-in-chief an d executive s to choose the most relevant papers and also helping authors...

Several questions of scientometrics parameters organization are considered. Two new indices for scientific works citation analysis are proposed. They provide more detailed and reliable scientific significance assessment of individual authors and scientific groups basing on the publication activity. (точнее их разработчиков