Open Access and Copyright: All articles published by Advanced Science are fully open access: immediately freely available to read, download and share. All articles are published under the terms of the Creative Commons Attribution License (CC-BY). The CC-BY license permits use, distribution and reproduction in any medium, provided the original work is properly cited and allows the commercial use...

In article 1600229, Shilong Wang, Rongrong Zhu, Yechang Qian, and co-workers investigate the anti-metastatic and anti-angiogenic effects of SiO2@LDH (LDH: layered double hydroxide) loaded with etoposide (VP16). SiO2@LDH has very suitable qualities as drug delivery agent and enhances the anti-metastatic action of VP16 both in vitro and in vivo. Enhanced anti-angiogenic efficacy is also proven wh...

Open Access and Copyright: All articles published by Advanced Science are fully open access: immediately freely available to read, download and share. All articles are published under the terms of the Creative Commons Attribution License (CC-BY). The CC-BY license permits use, distribution and reproduction in any medium, provided the original work is properly cited and allows the commercial use...

This study aims to explore the role of the SDF-1/CXCR4 axis in mediating BMSCs and SCI recovery. BMSCs were collected and SCI rat models were established. Wistar rats were assigned into the blank control, sham, SCI, SCI + BMSCs, SCI + BMSCs + SDF-1, SCI + BMSCs + AMD3100 (an inhibitor of SDF-1/CXCR4 axis) and SCI + BMSCs + SDF-1 + AMD3100 groups. Hind limb motor function was measured 7, 14, 21 ...

spinal cord injury (sci) actuate to complex cellular and molecular interactions within the central nervous system in a heave to repair the initial tissue damage. the pathophysiology of acute spinal cord injury (sci) involves primary and secondary mechanisms. neuroinflammation is an important secondary injury process in sci. the local inflammatory microenvironment within the injured spinal cord ...

the purpose of this study was to shed light on the identification of themes and sub-themes of the quality of life (qol) in iranian veterans with spinal cord injury (sci). studies have reported decreased qol in sci patients which encompass all aspects of their life. little is known about qol in sci veterans from iran. the aim of this qualitative study was to identify related aspects of such pati...

BACKGROUND The purpose of this study was to investigate the therapeutic effects and mechanisms of hyperbaric oxygen (HBO) treatment on rats following spinal cord injury (SCI). METHODS A total of 45 Sprague-Dawley (SD) rats were randomly divided into three groups. Sham-SCI group was surgically exposed but not subjected to the SCI procedure. SCI-control group was administered SCI and treated wi...

We show how the traditional protocol stack, such as TCP/IP, can be eliminated for socket based high speed communication within a cluster. The SCI shared memory interconnect is used as an example, and we demonstrate how existing applications can utilize the new technology without relinking. This is done by dynamically remapping the TCP/IP socket implementation to our high performance SCILAN sock...

Open Access and Copyright: All articles published by Advanced Science are fully open access: immediately freely available to read, download and share. All articles are published under the terms of the Creative Commons Attribution License (CC-BY). The CC-BY license permits use, distribution and reproduction in any medium, provided the original work is properly cited and allows the commercial use...