Abstract Background Inflammation is linked to elevated cardiovascular disease (CVD) risk in people with HIV (PWH) on antiretroviral therapy (ART). Fat attenuation index (FAI) a measure of peri-coronary inflammation that independently predicts CVD HIV-uninfected persons. Whether FAI associated soluble inflammatory markers unknown. Methods Plasma levels were measured 58 PWH and 16 controls withou...

Objective High vitreous levels of soluble (s)CD163 have been demonstrated in severe diabetic retinopathy (DR). The aim this study was to explore the predictive values plasma sCD163 and glycated haemoglobin (HbA1c) for DR progression adults with type 1 diabetes. Methods analyses design prospective. Fundus photography performed 2009 at follow-up (≤12 years later) were compared after being categor...

BackgroundThe pathogenesis of coronavirus disease 2019 (COVID-19) is still incompletely understood, but it seems to involve immune activation and dysregulation.ObjectiveWe examined the parameters different leukocyte subsets in COVID-19–infected patients relation severity.MethodsWe analyzed plasma levels myeloperoxidase (a marker neutrophil activation), soluble (s) CD25 (sCD25) T-cell immunoglob...

Recent developments in lipid mass spectrometry enable extensive lipid class and species analysis in metabolic disorders such as diabesity and metabolic syndrome. The minor plasma lipid class sphingosylphosphorylcholine (SPC) was identified as a ligand for lipid sensitive G-protein coupled receptors playing a key role in cell growth, differentiation, motility, calcium signaling, tissue remodelin...