BACKGROUND In aging societies such as that of Japan, it is important to characterize lifestyle-related factors that minimize the occurrence of silent brain infarction (SBI) among the middle aged population for preventing vascular dementia in older age. Little is known about the relationship between amount of coffee consumption and SBI. METHODS To assess the association between the amount of c...

In 2008, a World Health Organization multi-national clinical trial found screening and brief intervention (SBI) to be effective in reducing illicit drug use and many have called for its widespread dissemination. To gain policy support for widespread dissemination, however, a strong business case must be made to policymakers. In particular, policymaker concerns over implementation costs can act ...

Background Alcohol screening and brief intervention (SBI) programs have been shown to be effective in reducing risky alcohol consumption among primary care patients [1-3]. Although various implementation protocols exist, it can be difficult to launch and sustain SBI programs. A number of barriers exist, including those related to clinical workflow, the intake process, and the incorporation of p...

The Gram-positive bacterium Staphylococcus aureus, similar to other pathogens, binds human complement regulators Factor H and Factor H related protein 1 (FHR-1) from human serum. Here we identify the secreted protein Sbi (Staphylococcus aureus binder of IgG) as a ligand that interacts with Factor H by a-to our knowledge-new type of interaction. Factor H binds to Sbi in combination with C3b or C...

BACKGROUND Neurosurgical operations cause unavoidable damage to healthy brain tissues. Direct surgical injury as well as surgically induced oxidative stress contributes to the subsequent formation of brain edema. Therefore, we tested the neuroprotective effects of hydrogen (H2) in an established surgical brain injury (SBI) model in rats. MATERIALS AND METHODS Adult male Sprague - Dawley rats ...

since  clinical  manifestations  of  most  febrile  infants  younger  than  three  months  old  are nonspecific, differentiation of serious bacterial infection (sbi) from self-limiting viral illness is a significant challenge for pediatricians. this study was performed to assess the diagnostic value of white blood cell count (wbc), absolute neutrophil count (anc), interleukin -6 (il-6) and c-re...

BACKGROUND Fever accounts for 70% of all consultations with pediatricians and family physicians. Fever without an identifiable cause (<7 days' duration) and fever of unknown origin (FUO, ≥ 7 days' duration) are particularly challenging clinical situations. METHOD This article is based on a selective literature search for publications containing the term "pediatric fever management," with spec...

PURPOSE This study was conducted to determine the effect of two mouthrinses elmex and Listerine on plaque accumulation in 12-year-olds. MATERIAL AND METHODS 30 12-year-old children took part in the clinical study. They were divided into three groups. Group I (10 people) was given Listerine to home use. Group II (10 people) was given elmex to home use. Group III (10 people) did not receive any...

OBJECTIVE Abdominal visceral adiposity is related to risks for insulin resistance and metabolic perturbations. Magnetic resonance imaging (MRI) and computed tomography are advanced instruments that quantify abdominal adiposity; yet field use is constrained by their bulkiness and costliness. The purpose of this study is to develop prediction equations for total abdominal, subcutaneous, and visce...

Sorghum is an important C4 grain and grass crop used for food, feed, forage, sugar, and biofuels. In its native Africa, sorghum landraces often grow to approximately 3-4 meters in height. Following introduction into the U.S., shorter, early flowering varieties were identified and used for production of grain. Quinby and Karper identified allelic variation at four loci designated Dw1-Dw4 that re...