The edible seaweed Sargassum polycystum (SP) is traditionally used against several human diseases. This investigation evaluated the effects of two dietary doses of SP ethanolic and aqueous extracts on the pancreatic, hepatic, and renal morphology of type 2 diabetic rats (T2DM). T2DM was induced by feeding rats on high calorie diet followed by a low dose streptozotocin. Changes in the diabetic r...

Sulfated polysaccharides from marine algae are one of the commercially beneficial compounds with a range of pharmaceutical and biomedical applications. They are testified to be effective against free radicals and related health complications. This study aims to determine the antioxidant potential of the sulfated polysaccharide from Sargassum myriocystum, followed by its purification and structu...

Abstract Synthesis and characterization of sodium alginate from Sargassum aquifolium dan cinereum have been successfully performed. S. were collected the Dompu Islands, West Nusa Tenggara, Indonesia. Extraction was performed by acid pathway, due to cell disruption addition Na 2 CO 3 for extraction. The HCl convert into alginate, then transformed using NaOH. NaOCl IPA used purification. Physicoc...

Over the last decade, Caribbean has seen massive, episodic influxes of pelagic sargassum negatively impacting coastal ecosystems, people’s livelihoods and climate-sensitive sectors. Addressing this issue solely as a hazard proven extremely costly attention is slowly turning towards potential opportunities for reuse valorization. However, ‘sargassum crisis into gold’ not easy. In study we use mu...

In the course of our search for antimalarial leads from marine algae, four metabolites, sargaquinoic acid, sargahydroquinoic acid, sargaquinal and fucoxanthin, were isolated from the South African alga Sargassum heterophyllum. Fucoxanthin and sargaquinal showed good antiplasmodial activity toward a chloroquine-sensitive strain (D10) of Plasmodium falciparum (IC50 1.5 and 2.0 microM, respectivel...

An investigation of the natural products chemistry of the brown alga Sargassum asperifolium from the red sea yielded a new steroidal metabolite, 24-vinyl cholest-4-ene-24-ol-3-one, saringosterone (3), a known steroidal metabolite, 24-vinyl cholest-5-ene-3b,24-diol, saringosterol (4), and known diterpene with a hydroazulene skeleton, dictyone (1). The identification of the isolated metabolites w...