نتایج جستجو برای: sarcoma tumors
تعداد نتایج: 244044 فیلتر نتایج به سال:
Proximal-type epithelioid sarcoma is an aggressive variant of epithelioid sarcoma most often occurring in soft tissues of the proximal limbs, characterized by polygonal cells, marked nuclear atypia, and varied rhabdoid features. Malignant rhabdoid tumor is an aggressive, well characterized entity typically with rhabdoid morphology and involving the kidney of pediatric patients. Rarely, tumors w...
PURPOSE Ewing sarcoma is a tumor of the bone and soft tissue characterized by diffuse cell membrane expression of CD99 (MIC2). Single-site, surgically resectable disease is associated with an excellent 5-year event-free survival; conversely, patients with distant metastases have a poor prognosis. Noninvasive imaging is the standard approach to identifying sites of metastatic disease. We sought ...
between i 9h i and 1993,30 cases of primary cardiac tumors were diagnosed at the imam khomeini hospital. 20 patients were female and 10 were male, with an average age of 32 years (ranging from 17 days to 65 years of age). the mean duration of symptoms before diagnosis was 6 months, with dyspnea and palpitation being the most common symptoms (60%) and cardiac' murmurs the most usual signs (...
Brain Metastasis in Bone and Soft Tissue Cancers: A Review of Incidence, Interventions, and Outcomes
Bone and soft tissue malignancies account for a small portion of brain metastases. In this review, we characterize their incidence, treatments, and prognosis. Most of the data in the literature is based on case reports and small case series. Less than 5% of brain metastases are from bone and soft tissue sarcomas, occurring most commonly in Ewing's sarcoma, malignant fibrous tumors, and osteosar...
Sarcomas are rare malignant mesenchymal tumors for which there are limited treatment options. One potential molecular target for sarcoma treatment is the Src tyrosine kinase. Dasatinib (BMS-354825), a small-molecule inhibitor of Src kinase activity, is a promising cancer therapeutic agent with p.o. bioavailability. Dasatinib exhibits antitumor effects in cultured human cell lines derived from e...
Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical disease are helpful in selecting therapeutics with the most promise of positive clinical impact. Human Ewing/PNET sarcoma cell lines developed...
human herpes virus 8 (hhv8) causes kaposi’s sarcoma, a common cancer among aids patients. it is proposed that this virus plays a role in formation of some blood vessel and lymphoma tumors. this study aimed to investigate the frequency of kshv among benign and malignant breast tumors. a total of 24 carcinomas and 24 fibroadenomas paraffin embedded tumoral tissue samples were obtained from the pa...
ZC3H7B-BCOR high-grade endometrial stromal sarcomas: a report of 17 cases of a newly defined entity.
High-grade endometrial stromal sarcoma likely encompasses underrecognized tumors harboring genetic abnormalities besides YWHAE-NUTM2 fusion. Triggered by three initial endometrial stromal sarcomas with ZC3H7B-BCOR fusion characterized by high-grade morphology and aggressive clinical behavior, we herein investigate the clinicopathologic features of this genetic subset by expanding the analysis t...
a survey of malignant lymphoid tumors among iranians the frequency. histopathologic features, and clinical aspects of malignant lymphoid tumors. among iranians arc discussed on the basis of 68,000 consecutive biopsies and 1917 autopsies performed over a twenty.five years period in the department of pathology at teheran university. of the 5814 lymph nodes examined on biopsy, 1368 (23%) showed ma...
The Ewing sarcoma family of tumors (ESFT) consists of a group of tumors characterized by morphologically similar round-cell neoplasm and by the presence of a common chromosomal translocation. Although rare, such tumors constitute the third most frequent primary sarcoma of bone after osteosarcoma and chondrosarcoma. ESFT most commonly affects young children and adolescents. Because most patients...
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