This paper presents a numerical investigation on the plastic forming of doubly curved surfaces aluminum foam sandwich panel (AFSP). A mesoscopic 3D Voronoi model that can describe structure closed-cell relatively realistically was established, and series simulations using with core were conducted two typical including spherical saddle-shaped AFSPs to analyze deformation behaviors defects in det...

This work studies the behaviour of sandwich panels made woven carbon/epoxy face-sheets and agglomerated cork as core material subjected to impacts at intermediate velocities, below perforation velocity panel. Agglomerated was selected an eco-friendly alternative traditional synthetic polymeric foams. A nonlinear/explicit finite element model implemented study problem. Continuous damage models w...

High-power and lightweight photovoltaic (PV) modules are suitable for building-integrated (BIPV) systems. Due to the characteristics of installation sites, BIPV solar limited by weight area. In this study, we fabricated glass-free shingled-type PV with an area 1040 mm × 965 mm, which provide more conversion power compared conventional at same installed Further, employed ethylene tetrafluoroethy...

Adnectins™ are a new family of therapeutic proteins based on the 10th fibronectin type III domain, and designed to bind with high affinity and specificity to therapeutically relevant targets. Adnectins share with antibody variable domains a beta-sheet sandwich fold with diversified loops, but differ from antibodies in primary sequence and have a simpler, single-domain structure without disulfid...

The structural / -hydrolase fold is characterized by a -sheet core of five to eight strands connected by -helices to form a / / sandwich. The superfamily members, exemplified by the cholinesterases, diverged from a common ancestor into a number of hydrolytic enzymes displaying a wide range of substrate specificities, along with proteins with no recognized hydrolytic activity. In the enzymes, th...

The fungal ribonuclease RNase T1 has been co-crystallized with its inhibitor 2'-guanylic acid and was analyzed by X-ray diffraction. The enzyme is folded into an a-helix 4.5 turns long, which is covered by a four-stranded antiparallel B-sheet. Specific recognition of guanine occurs with two hydrogen bonds between main chain peptide groups of Asn43 and Asn44 and the 0(6) and N(1)-H of guanine, a...

Vitamin D Receptor (VDR) belongs to the nuclear receptor (NR) superfamily. Whereas the structure of the ligand binding domain (LBD) of VDR has been determined in great detail, the role of its amino acid residues in stabilizing the structure and ligand triggering conformational change is still under debate. There are 13 α-helices and one β-sheet in the VDR LBD and they form a three-layer sandwic...

Most poxviruses, including variola, the causative agent of smallpox, express a secreted protein of 35 kDa, vCCI, which binds CC-chemokines with high affinity. This viral protein competes with the host cellular CC-chemokine receptors (CCRs), reducing inflammation and interfering with the host immune response. Such proteins or derivatives may have therapeutic uses as anti-inflammatory agents. We ...

How to orient polymers homeotropically in thin films has been a long-standing issue in polymer science because polymers intrinsically prefer to lie down. Here we provide a design principle for polymers that are processable into a 2D homeotropic order. The key to this achievement was a recognition that cylindrical polymers can be designed to possess oppositely directed local dipoles in their cro...

The Centre for Sustainable Energy Systems at the Australian National University is working on the development of low cost durable mirrors for large paraboloidal dish concentrators and for smaller trough concentrators photovoltaic systems. Both concepts utilize a robust Glass on Metal Laminate (GOML) technology for the mirror surface. The dish mirror panels use the GOML material in a sandwich co...