introduction: in this study the automatic separation of oral and salivary gland activity and spontaneous secretion by means of factor analysis for quantitative salivary gland scintigraphy is introduced. methods: after intravenous administration of 99mtc sodium pertechnetate, dynamic scintigraphy was performed. 20 minutes after tracer application 2 ml of lemon juice was delivered to stimulate t...

Salivary duct carcinoma (SDC) is an uncommon, aggressive tumour, which carries a poor prognosis. SDC affects the major salivary glands, usually occurring in the parotid gland. A 76-year-old male patient presented with right-sided nasal obstruction and rhinorrhoea. A polypoidal mass was seen in the right inferior turbinate mimicking a benign neoplasm. Histological examination following wide exci...

BACKGROUND With the 2005 WHO classification of salivary gland tumours and its increasingly recognized diagnostic entities, the frequency of adenocarcinoma (NOS) has decreased significantly. CASE PRESENTATION This paper describes a fast growing adenocarcinoma (NOS), originating from the minor salivary glands of the left buccal mucosa with a rapid onset of multiple local and distant metastases,...

background: salivary gland tumors are among malignancies that have high recurrence rate. immune responses in salivary gland tumors have not been well elucidated. t helper type 1 (th1) and th2 cytokines have been reported to play a role in the outcome of head and neck cancers. objective: to evaluate the serum levels of interferon gamma (ifn- γ), as the hallmark of th1 cytokines, and interleukin-...

OBJECTIVE To evaluate the incidence of salivary gland pleomorphic adenoma in Jordanian patients. METHODS The retrospective study involved histopathological reports of 62 patients diagnosed to have pleomorphic adenoma from salivary glands between 2000 and 2008 at King Hussein Medical Centre and the peripheral military hospitals of the Royal Medical Services, Jordan. The files were evaluated. S...

Introduction: Chronic sclerosing sialadenitis is a relatively uncommon disorder of the salivary gland. Because of its clinical similarity to a salivary gland neoplasm, this condition has been known as Kuttner tumor and is classified as a tumorlike lesion. Case Report: This is the first reported case of bilateral Kuttner tumor of the submandibular glands in Iran. It was initially diagnosed as...

BACKGROUND Non-obese diabetic (NOD) mice exhibit autoimmune diabetes and Sjögren's-like syndrome. OBJECTIVE To test whether a treatment that reverses end-stage diabetes in the NOD mouse would affect their Sjögren's-like syndrome. METHODS NOD mice have a proteasome defect. Improperly selected naive T cells escape, but can be killed by reintroducing major histocompatibility complex class I se...

OBJECTIVE To establish distribution frequency and demographic characteristics of salivary gland tumours (SGT) in order to identify possible risk profiles. DESIGN OF STUDY The present report constitutes an eight year retrospective study (January 2000-August 2007). The archives of the Clinical and Experimental Pathology Laboratory (Graduate and Research Division, Dental School, National Autonom...

Solitary fibrous tumours are spindle-cell neoplasms that usually occur in the pleura and peritoneum, and rarely involve the oral mucosa. We report a 30-year-old man with a large solitary fibrous tumour on the buccal mucosa that resembled a salivary gland neoplasm. The lesion was excised and has not recurred.

Acinic cell carcinoma is a rare breast tumour belonging to salivary gland-like tumours of the breast. They are "triple-negative" breast cancers even if their biological behaviour seems to be more favourable. Herein we present an acinic cell carcinoma arising on a background of typical and atypical microglandular adenosis in a 58-year-old woman, along with a review of the literature.