objective: the aim of the present study was to evaluate unstimulated salivary flow rate and oral symptoms in menopausal women. materials and methods: a total of 200 individuals including 100 women in their menopause (case group) and 100 men in the same age range (control group) participated in this analytic descriptive investigation. none of the patients were being treated for any systemic dise...

background and aims. various morphologies are seen in different salivary gland tumorsor within an individual tumor, and the lesions show divers biological behaviors. experimental results support the hypothesis that increased crkii proto-oncogene is associated with cytokine-induced tumor initiation and progression by altering cell motility signaling pathway. the aim of this study was to assess t...

background: salivary gland tumors are among malignancies that have high recurrence rate. immune responses in salivary gland tumors have not been well elucidated. t helper type 1 (th1) and th2 cytokines have been reported to play a role in the outcome of head and neck cancers. objective: to evaluate the serum levels of interferon gamma (ifn- γ), as the hallmark of th1 cytokines, and interleukin-...

Aim and objective: The aim of the study is to associate salivary calcium and phosphate in oral health. Background: Salivary glandular secretion which constantly bathes the teeth and oral mucosa. Presence of saliva is vital for healthy oral tissue. Positive correlation has been shown in salivary calcium and phosphate and oral health. Reason: To associate role of salivary calcium and phosphate in...

background and aims. mast cells are one of the characteristic factors in angiogenesis, growth, and metastatic spread of tumors. the distribution and significance of mast cells in many tumors have been demonstrated. however, few studies have evaluated mast cell infiltration in salivary gland tumors. in this study, mast cell counts were evaluated in benign and malignant salivary gland tumors. mat...

background and aims. salivary gland tumors are rare and specific lesions. there are differences in the incidence and frequency of salivary tumors in both minor and major salivary glands in different countries. this study was carried out to determine the prevalence of major and minor salivary gland tumors in ahvaz in the south of iran. materials and methods. all the cases, recorded in imam khome...

OBJECTIVES To determine the expression level of the Wnt components-WIF1 (Wnt inhibitory factor 1), WNT1, and beta-catenin-in salivary gland tumor cells and to investigate the mechanisms that contribute to activation of the Wnt pathway in human salivary gland tumors. DESIGN The expression of WIF1, WNT1, and beta-catenin in salivary gland normal tissue and tumor cell lines was analyzed by rever...

Saliva constitutes an important role in maintaining the health of the oral cavity. It helps in lubrication, mastication, and has effective antimicrobial action. In prosthodontics, saliva plays a main role in retention of the denture. Hyposalivation is a main complication in diabetes, radiotherapy, chemotherapy, sjogren syndrome, certain systemic conditions and patients with maxillofacial defect...

background: nitric oxide (no), a highly reactive radical, participates in the nonspecific natural defense mechanism of the oral cavity. aims and objectives: the present study was attempted to evaluate the salivary no levels in 4–5 year‑old children with early childhood caries (ecc). the objective of the present study was to assess the salivary no concentration in children with different caries ...

background. visfatin (pre-b-cell colony-enhancing factor) is a salivary biomarker secreted from a variety of cells and is thought to have some proinflammatory and immune-modulating effects. this study compared salivary concentrations of visfatin in patients with chronic periodontitis and periimplantitis and healthy individuals. methods. in this cross-sectional and descriptive trial, patients we...