background and objectives: virosomes are virus like particles (vlp) assembled in-vitro. influenza virosomes maintain the cell binding and membrane fusion activity of the wild type virus but are devoid of viral genetic material or internal proteins. influenza virosomes mimic the natural antigen presentation route of the influenza virus. materials and methods: virosomes were prepared by membrane ...

conclusions the results of this work demonstrated that the subcellular distribution of pfdn1 was altered in the rabv-infected n2a cells and colocalized with the n protein of rabv in the nbl structures. results confocal microscopy showed that pfdn1 was colocalized with the n protein of rabv in the infected n2a cells and was mainly recruited to the characteristic negri-body-like (nbl) structures ...

zika virus is an arbovirus identified first time in 1947 in uganda. zika epidemic is a threat far greater than the ebola outbreak. the world health organization has urged asian countries to be vigilant about the risk of spreading zika virus and preventive measures to control it. in iran, 64 species of mosquitoes from culicidea family have been reported three of which belong to the aedes genus, ...

a total of 698 blood and serum specimens from residents of 13 iranian communities were examined by plaque reduction neutralization test for antibodies to west nile virus. in general, infection rates in the north of the country were low while higher rates were observed among residents of central and southwestern iran. the highest prevalence of infection was found among residents of khuzestan pro...

results patients’ age ranged from 15 to 65 years (mean = 35.54 ± 14.85). thirty four (1.0%) of the subjects were positive for hbsag, of whom, 2.9 % (1 of 34 cases) were also positive in pcr-based screening. elisa tests for hbeag, hbeab, and hbcab igm were positive in one (2.9 %), 27 (79.4%) and one (2.9 %) cases, respectively. conclusions according to our results, hbsag was positive in 0.53 of ...

high morbidity and mortality of influenza virus infection makes it an important disease world-wide. mouse is a very well-studied animal model for this disease with similar manifestation to human disease. it would be desirable to induce mucosal as well as circulating immune responses to obtain protection from infection and to decrease the spread of the virus. cell mediated immunity (proliferativ...

background : to analyze serologic markers of hepatitis g virus (gbv-c) infection in iranian blood donors and two major groups of multitransfused patients, hemophiliacs and thalassemics. methods :nine hundred and five serum samples collected from the volunteer blood donors and two patient groups under the study were tested for the presence of antibodies to the gbv-c antigen (anti e2 ) by an elis...

Background: Approximately 600,000 deaths occur every year as a result of the acute and chronic consequences of hepatitis B virus infection. Ten different hepatitis B virus genotypes have been identified with distinct geographical distributions. Different clinical outcomes, including the rate of mutations, development of hepatocellular carcinoma, chronicity, response to treatment, transplantatio...