From ancient times, saffron, the flower of the plant Crocus sativus L., is widely used as a traditional medicine to promote health and fight disease. Crocus sativus is cultivated in different parts of the world such as Greece, Spain and, mainly, Iran. In view of its wide range of medicinal uses, saffron has submitted to extensive phytochemical and biochemical studies and a variety of biological...

Aims: Previous investigations have confirmed the anti-inflammatory and analgesic effects of aqueous-ethanol extract of saffron on formalin induced pain in small male mice. Since there is difference between ethanol and aqueous-ethanol extract of saffron, this study was performed in order to evaluate the effect of ethanol saffron extract on acute and chronic pain in small male mice. Materials & M...

INTRODUCTION Chemoprevention strategies are very attractive and have earned serious consideration as potential means of controlling the incidence of cancer. An important element of anticancer drug development using plants is the accumulation and analysis of pertinent experimental data and purported ethnomedical (folkloric) uses for plants. The aim of this review is to provide an updated overvie...

BACKGROUND Saffron is the dried stigma of Crocus sativus L. flower which commonly used as a natural remedy to enhance health and even fights disease in the Middle-East and Southeast Asian countries. METHODS This study was aimed to investigate protective effect of saffron extract and crocin in fatty liver tissue of high-fat diet induced obese rats. A total of 36 healthy male Sprague Dawley r...

(ACR) is an industrial neurotoxic chemical that has been -rich foods cooked at high temperature. in acrylamide-induced neurotoxicity. Seven seven groups served as control group, groups treated selenium (0.04 mg/kg), saffron 30mg/kg, and Acrylamide (50 mg/kg) for 8 days, and groups before and Only weak and transient DNA damage was recorded in the brain The treatment in combination of saffron

OBJECTIVE To evaluate herbal medicines, other than St. John's wort, in the treatment of depression. DATA SOURCES/SEARCH METHODS: A computer-based search of Medline, Cinahl, AMED, ALT Health Watch, Psych Articles, Psych Info, Current Contents databases, Cochrane Controlled Trials Register, and Cochrane Database of Systematic Reviews, was performed. Researchers were contacted, and bibliographies ...

BACKGROUND Several studies have supported the antidepressant effects of curcumin (from the spice turmeric) and saffron for people with major depressive disorder. However, these studies have been hampered by poor designs, small sample sizes, short treatment duration, and similar intervention dosages. Furthermore, the antidepressant effects of combined curcumin and saffron administration are unkn...

Saffron corms are attacked by a wide variety of arthropod pest species and mites one them. Among Arachnida class bulb mite causes considerable damage to saffron crop presence this is regular feature in its cultivation. To record the occurrence mite, field study was conducted at different growing areas Kashmir. For biology pest, laboratory Department Entomology, Faculty Horticulture, Sher-e-Kash...

OBJECTIVES We have investigated the effect of a saffron supplement, given at a dose of 100 mg/kg, on prooxidant-antioxidant balance (PAB) in individuals with metabolic syndrome. MATERIALS AND METHODS A randomized, placebo-controlled trial design was used in 75 subjects with metabolic syndrome who were randomly allocated to one of two study groups: (1) the case group received 100mg/kg saffron ...

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