Sepsis-associated encephalopathy (SAE) is characterized as brain dysfunction associated with sepsis. In this study we sought to investigate the effects of resveratrol in mice with SAE, as well as its effects in NLRP3 inflammasome and IL-1β, which were critical in the pathogenesis of SAE. SAE was induced in mice via cecal ligation and puncture (CLP), and resveratrol was administered at two doses...

Recent methodological advances have made it possible to investigate how children process language and arrive at sentence-level meaning on-line. For example, eye-tracking enables analysis of how individual words and morphemes are interpreted during comprehension. This allows results from traditional off-line measures to be integrated with on-line measures leading to a more complete understanding...

PURPOSE We aimed to compare clinical outcomes and early adverse events of operative management (OM), nonoperative management (NOM), and NOM with splenic artery embolization (SAE) in blunt splenic injury (BSI) and identify the prognostic factors. METHODS Medical records of 136 consecutive patients with BSI admitted to a trauma center from 2005 to 2010 were retrospectively reviewed. Patients we...

Over the latest few years, most of the major telephony and services providers have got their attention on the LTE/SAE solution, in the attempt of getting the most bandwidth and features at the least implementation and operating price. One of the major challenges that 3GPP, the creator of LTE/SAE architecture, has faced is the IMS integration with SAE. The latest standard version available at th...

A resilient tracking circuit for suppressing the timing variation of SRAM sense amplifier enable (SAE) signal is proposed. Pipelined replica bitline technique is used to favour the desired design. Simulation results show that the cycle time is reduced by ∼27% owing to ∼70% reduction of the standard deviation of SAE at a 1.05V supply voltage in 28 nm CMOS technology with four-stage pipeline.

Staphylococcus aureus is a leading cause of infective endocarditis in people who inject drugs (PWID). The management of S aureus endocarditis (SAE) in PWID can be problematic. The objective of this retrospective observational study was to assess the epidemiology, clinical characteristics, and mortality of S aureus endocarditis (SAE) in PWID in Stockholm, Sweden.The Department of Infectious Dise...

OBJECTIVES To determine the proportion of maternal and perinatal mortality and morbidity cases, identified by the Perinatal and Maternal Mortality Review Committee (PMMRC), that are also reported within the annual serious adverse events (SAEs) reports published by the Health Quality and Safety Commission (HQSC). SETTING Nationally collated data from the PMMRC and HQSC, New Zealand. PARTICIP...

OBJECTIVE Lower pregnancy rates of in vitro matured oocytes compared to those of in vivo stimulated cycles indicate that optimization of in vitro maturation (IVM) remains a challenge. Reduced developmental competence of in vitro matured oocytes shows that current culture systems for oocyte maturation do not adequately support nuclear and/or cytoplasmic maturation. Therefore this study evaluates...