Dye-diffusion test for semiquantitative staphylocoagulase assay. Ever since 1903, when Leob reported the ability of staphylococci to produce coagulase, an enzyme capable of clotting plasma, numerous workers have demonstrated the practical applicability of this phenomenon as an indicator of potential pathogenicity of these organisms. Two general procedures for coagulase determination are the tub...

The use of resins as a basis for "tubeless test meals " has made the unpleasant experience of aspiration of gastric contents unnecessary in many cases. A substance incorporated in the resin is released in the stomach only in the presence of free hydrochloric acid. This substance is then absorbed into the blood and excreted in the urine. Originally quinine was used in the test, and estimated flu...

Florence Rena Sabin [5] had successful careers as both a researcher and public health reformer. When Johns Hopkins University [6] Medical School opened, accepting women and men on the same basis, Sabin was one of the first to enter. After the successful completion of her MD degree, Sabin went on to become the first female faculty member and later full-time professor at Johns Hopkins. From 1924?...