Induction of an adaptive, or antigen specific, immune response is critical for eliminating most infections. Pathogen clearance is accomplished primarily, by the actions of CD4+ T cells through their ability to recognize foreign antigens presented at the cell surface by major histocompatibility class II (MHC II) molecules. Consequently, the capacity to regulate expression of MHC molecules is ess...

The nucleotide sequences of all genome segments of the Nilaparvata lugens reovirus (NLRV), which is found in the brown planthopper Nilaparvata lugens, have been determined and some genes have been assigned to structural and functional proteins. The genome of NLRV consists of 28 699 nucleotides and contains at least 11 large open reading frames (ORFs). The genome of NLRV is the largest among vir...

Climate change is predicted to increase sea level and cause saline intrusion of coastal freshwaters. This will have consequences for freshwater organisms inhabiting such areas; developmental phenotypic plasticity may facilitate the persistence of freshwater species under such scenarios of increased salinity. Here we investigated developmental plasticity under different salinity treatments (S = ...

A 75-year-old woman was admitted to our hospital because of a poor glycemic control. She was found to have Cushingoid feature and dynamic endocrine tests showed elevated plasma ACTH and cortisol levels, lack of their circadian rhythm, non-suppressibility to high-dose dexamethasone, responsiveness to CRH, but not to DDAVP, and suppression to octreotide. Pituitary MRI showed an equivocal small le...

We show that Y. Prokhorov’s “Simple Finite Subgroups of the Cremona Group of Rank 3” implies that, over any field of characteristic 0, the essential dimensions of the alternating group, A7, and the symmetric group, S7, are 4.

AIM Wearable technology interfaces with normal human movement and function, thereby enabling more efficient and adaptable use.We developed a wearable display system for use with intra-operative neuronavigation for brain tumor surgery. MATERIAL AND METHODS The Google glass head-up display system was adapted to surgical loupes with a video-streaming integrated hardware and software device for d...