نتایج جستجو برای: s thrombasthenia
تعداد نتایج: 711432 فیلتر نتایج به سال:
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Glanzmann’s thrombasthenia (GT) is an uncommon congenital disease due to a qualitative or quantitative anomaly of the glycoprotein complex GPIIb/IIIA, resulting in defective platelet aggregation. In pregnant women, this bleeding disorder could lead severe haemorrhages and may require aggressive treatment with combined therapy, including concentrates, anti-fibrinolytics recombinant activated coa...
Glanzmann's thrombasthenia is a bleeding disorder characterized by a decrease or absence of the functional platelet membrane glycoprotein (GP) complex, GPIIb/IIIa (alpha IIb beta 3). We describe a new deletion-insertion mutation in the GPIIb gene causing type I Glanzmann's thrombasthenia in two siblings of a consanguineous Iranian-Jewish family. The proband's platelets bound more antibodies aga...
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