BACKGROUND Among the vascular involvements of Takayasu arteritis, a supra-valvular aortic stenosis has been reported very rarely. We report a case of surgically corrected, supra-valvular aortic stenosis caused by Takayasu arteritis. CASE PRESENTATION A 32-year-old female was diagnosed with supra-valvular aortic stenosis by transthoracic echocardiography for the evaluation of cardiac murmur wi...

The differential of scalp ulceration in older patients should include several causes, such as herpes zoster, irritant contact dermatitis, ulcerated skin tumors, postirradiation ulcers, microbial infections, pyoderma gangrenosum, and giant cell arteritis. Scalp necrosis associated with giant cell arteritis was first described in the 1940s. The presence of this dermatological sign within giant ce...

Arterial inflammatory responses are thought to be a significant component of atherosclerotic disease. We describe here, using a transgenic approach, the mutual perpetuation of immune-mediated arterial inflammation and cholesterol-induced atherosclerosis. Mice expressing the bacterial transgene beta-galactosidase exclusively in cardiomyocytes and in smooth muscle cells in lung arteries and the a...

Comment A fatal outcome in patients with giant cell arteritis has been poorly recognised, and previous reports have generally been case reports or necropsy studies.4 The necropsy rate is low in many countries, and microscopic examinations of arteries in patients dying from vascular disorders are not routine, especially in elderly people. Hence, giant cell arteritis may be concealed among the ca...

We report a Caucasian female who presented with simultaneous erythema nodosum and pyoderma gangrenosum due to underlying Takayasu's arteritis. Takayasu's arteritis is a chronic large vessel vasculitis of unknown cause. The disease has a worldwide distribution but is most commonly seen in Asian populations. There is a strong predilection for young females. The clinical presentation is variable, ...

Management of Takayasu's arteritis of the left main coronary artery (LMCA) is difficult because of the possibility of restenosis. Clinically significant stenotic lesions must be considered anatomical correlation. Many studies have reported that the management of stenotic lesions of the LMCA with endoluminal stenting and balloon angioplasty and de-novo stenting is safe and effective for patients...

689–90. 16 Corrao S, Salli L, Arnone S, Scaglione L, et al. Echodoppler abnormalities in patients with rheumatoid arthritis without clinically evident cardiovascular disease. Eur J Clin Invest 1996;26:293–7. 17 Slack D, Waller B. Acute congestive heart failure due to the arteritis of rheumatoid arthritis. Early diagnosis by endomyocardial biopsy. Angiology 1986;6:477–81. 18 Banks MJ, Flint EJ, ...

Takayasu's arteritis and inflammatory bowel disease are rarely found together, although the number of cases reported in the literature is increasing. Takayasu's arteritis has been studied in 31 patients from the Arab world but in none of them was it associated with Crohn's disease. We report the case of a Saudi woman previously diagnosed with Crohn's disease who subsequently developed Takayasu'...

Polymyalgia rheumatica is a clinical syndrome affecting middle-aged and elderly persons and is characterized by periarthritic and muscular pain and stiffness particularly in the shoulder and hip girdles. Systemic symptoms are present, the erythrocyte sedimentation rate (E.S.R.) is greatly elevated, and the Waaler-Rose test is almost invariably negative. Suppression of symptoms with corticostero...