1 Musculoskeletal Research Group, Institute of Anatomy, Ludwig-Maximilian-University Munich, 80336 Munich, Germany 2 Nutrition and Metabolism Research Group, WALTHAM Centre for Pet Nutrition, Waltham on the Wolds, Melton Mowbray, Leicestershire LE14 4RT, UK 3 Musculoskeletal Research Group, Division of Veterinary Medicine, School of Veterinary Medicine and Science, Faculty of Medicine and Healt...

Introduction Lycopene (C40H56), as a unsaturated red-pigmented linear carotenoid, has a molecular weight of 536.85 Da, and 11 conjugated and 2 non-conjugated double bonds; it is lipophilic and therefore more soluble in organic solvents (1-3). Lycopene is a lipid-soluble antioxidant and has been inversely associated with lipid peroxidation, comprising low-density lipoprotein oxidation and reduce...

OBJECTIVE To develop concise, up-to-date, patient-focused, evidence-based, expert consensus guidelines for the management of knee osteoarthritis (OA), intended to inform patients, physicians, and allied healthcare professionals worldwide. METHOD Thirteen experts from relevant medical disciplines (primary care, rheumatology, orthopedics, physical therapy, physical medicine and rehabilitation, ...