نتایج جستجو برای: rorγt
تعداد نتایج: 603 فیلتر نتایج به سال:
Sox (SRY-related high-mobility-group (HMG)-box) transcription factors, which are comprised of 20 genes containing a conserved HMG DNA-binding domain, are divided into 8 groups (from A to H) according to structural homologies [reviewed in 1-2]. SoxC group, which is composed of Sox4, Sox11, and Sox12, has a HMG box domain and a transactivation domain and plays important roles in the development o...
Materials and methods We have enrolled 58 JIA patients (polyarticular and oligoarticular disease) and 69 healthy controls. We examined CD4+CD25+FOXP3+ percentage (flow cytometry), FOXP3 and RORγt mRNA (RT-PCR) in peripheral blood mononuclear cells (PBMCs), and in synovial fluid mononuclear cells (SFMCs). FOXP3 median fluorescence intensity (MFI) of CD4+ T cells was also determined. Interleukin-...
Lymphoid tissue-inducer cells are hematopoietic cells essential for the organogenesis of several lymphoid structures during both fetal and adult life, whereas natural killer cells are key effector lymphocytes of the innate immune system. A series of recent reports has identified RORγt(+)NKp46(+) interleukin-22-producing cells in gut and tonsils that share features with both lymphoid tissue-indu...
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