We observed that human rhabdomyosarcoma (RMS) cells highly express a tissue factor that promotes thrombin formation, which indirectly and directly affects RMS progression. First, we found that thrombin activates platelets to generate microvesicles (PMV), which transfer to RMS cells' alpha2beta3 integrin and increase their adhesiveness to endothelial cells. Accordingly, RMS cells covered with PM...

Temperature fluctuations have been measured in a turbulent, natural gas-fueled, piloted jet diffusion flame with a fuel jet exit Reynolds number of 9700, using broadband Coherent Anti-Stokes Raman Spectroscopy (CARS) nitrogen thermometry with a best spatial resolution of 0.9 mm. Radial profiles of mean temperature and root mean square (rms) temperature fluctuations have been acquired and temper...

Spherical harmonic synthesis (SHS) of gravity field functionals at the Earth’s surface requires the use of heights. The present study investigates the gradient approach as an efficient yet accurate strategy to incorporate height information in SHS at densely-spaced multiple points. Taylor series expansions of commonly used functionals quasigeoid heights, gravity disturbances and vertical deflec...

Rhabdomyosarcoma (RMS) is a malignant skeletal muscle neoplasm. RMS can occur anywhere in the body and is the most common childhood sarcoma (1). Pediatric RMS is an aggressive neoplasm with deregulated cell cycle checkpoints, high genome instability, and oncongene ampli ication such as MYC family members (2). However, RMS rarely occurs in adults. Moreover, sarcomas of the kidney are rare soft t...

We define Recursive Matrix Systems (RMS), a highly parameterizable formalism that allows for a clear separation of various kinds of recursion. One instance of RMS, namely context-free RMS with two rows and a specific reading interpretation turns out to be weakly equivalent to TAG. This allows for the transfer ofresults from TAGs to this dass of RMS. Furthermore, the equivalence proof is constru...

A Computer-Aided-Test (CAT) platform has been integrated in the Cadence Design Framework Environment for the evaluation of analogue/mixed-signal/RF Built-In-Self-Test (BIST) techniques. It comprises tools for statistical modelling of circuit performances, fault simulation, test generation and test optimization. The fault modelling and fault injection tools are simulator-independent, thus they a...

Rhabdomyosarcomas (RMS) bear a morphological resemblance to developing striated muscle. It has been reported that two histologically distinct subtypes of RMS, embryonal and alveolar, behave differently in many clinical aspects, such as age distribution, primary site, and prognosis. We have investigated the expression of various genes, which are preferentially expressed in normal muscle tissue o...

Rhabdomyosarcomas (RMSs) are frequently characterized by bone marrow involvement. Recently, we reported that human RMS cells express the CXC chemokine receptor-4 (CXCR4) and postulated a role for the CXCR4 stromal-derived factor (SDF)-1 axis in the metastasis of RMS cells to bone marrow. Because RMS cells also express the tyrosine kinase receptor c-MET, the specific ligand hepatocyte growth fac...

The objective of this study was to investigate whether stressful experience during early postnatal period may influence morphological characteristics of the rat neurogenic pathway--the rostral migratory stream (RMS) and proliferation of neuronal precursors in three successive areas of the RMS: in the vertical arm, the elbow and the horizontal arm. To induce stress, the pups were subjected to re...

Rhabdomyosarcoma (RMS) is an aggressive family of soft tissue tumors that most commonly manifests in children. RMS variants express several skeletal muscle markers, suggesting myogenic stem or progenitor cell origin of RMS. In this review, the roles of both recently identified and well-established microRNAs in RMS are discussed and summarized in a succinct, tabulated format. Additionally, the s...