BACKGROUND The fat embolism syndrome is clinically characterized by dyspnea, skin petechiae, and neurological dysfunction. It is associated mainly with long bone fracture and bone marrow fat passage to the systemic circulation. An intracardiac right-to-left shunt (RLS) could allow larger fat particles to reach the systemic circulation. Transcranial Doppler can be a useful tool to detect both RL...

BACKGROUND Restless legs syndrome (RLS) is a usually chronic disorder accompanied by clinically relevant psychosocial impairment. To date, no psychologically based approach is available to improve the coping strategies and quality of life of RLS sufferers. OBJECTIVE To develop cognitive behavioural therapy tailored to this disorder (the RELEGS coping therapy programme) and present the results...

BACKGROUND Restless legs syndrome (RLS) may be associated with increased morbidity and mortality among end-stage renal disease (ESRD) patients; however, it is a disorder that is neglected in dialysis centers. OBJECTIVES The goal of this study was to investigate the clinical factors associated with RLS among ESRD patients. PATIENTS AND METHODS This cross-sectional study was conducted on ESRD...

PURPOSE Attention deficit hyperactivity disorder (ADHD) is a common disorder in school-aged children. Patients with restless legs syndrome (RLS) often present with ADHD symptoms and vice versa. This study was the first to attempt to identify the prevalence of RLS and sleep problems in children with ADHD in Korea. METHODS Patients diagnosed with ADHD were asked to complete a sleep questionnair...

INTRODUCTION Restless legs syndrome (RLS) is a prevalent sleep disorder affecting quality of life and is often comorbid with other neurological diseases, including peripheral neuropathy. The mechanisms related to RLS symptoms remain unclear, and treatment options are often aimed at symptom relief rather than etiology. RLS may present in distinct phenotypes often described as "primary" vs. "seco...

OBJECTIVES Restless legs syndrome (RLS) occurs in polyneuropathy with small fiber involvement, possibly as a peculiar form of neuropathic pain; however, the relationship between pain and RLS has been poorly investigated in polyneuropathy. DESIGN, SETTING, AND PATIENTS We evaluated retrospectively the occurrence of RLS in 102 consecutive patients with polyneuropathy manifesting with neuropathi...

Reduced brain iron is strongly associated with restless legs syndrome (RLS). Oral iron supplements are commonly recommended for RLS but are largely ineffective due to poor absorption and poor tolerability at required doses. Intravenous iron dextran has been shown to increase brain iron content. Surprisingly only a few reports have ever presented data on the clinical effect of high dose intraven...

A variation in right atrial and pulmonary arterial pressure might result in a shunt dynamic across a patent foramen ovale (PFO). In the present study we tested if peak exercise facilitates a restoration of right to left shunt (RLS) in stroke patients who demonstrated a functional PFO closure (no evidence of RLS across an initially demonstrated PFO). In stroke patients with PFO demonstrating a f...

This thesis introduces analysis tools for improving the current state of the art of heuristics for the Maximum Clique (MC) problem. The analysis focusses on algorithmic building blocks, on their contribution in solving hard instances of the MC problem, and on the development of new tools for the visualisation of search landscapes. As a result of the analysis on the algorithmic building blocks, ...

restless leg syndrome (rls) is a common cause of painful legs. the leg pain of restless leg syndrome typically eases with motion of the legs and becomes more noticeable at rest. stress or emotional upset can make symptoms worse. the purpose of the present study was to examine the relationship of emotional disturbance and quality of life to the severity of rls. using a descriptive-correlational ...