As a key mediator of type I interferon (IFN) (IFN-alpha/beta) responses, IFN regulatory factor 7 (IRF7) is essential to host immune defenses. Activation of IRF7 generally requires virus-induced C-terminal phosphorylation, which leads to its nuclear accumulation and activation of target genes. Here we use the Epstein-Barr virus (EBV) oncoprotein LMP1, which activates IRF7, to identify factors in...

Ribosome-inactivating proteins (RIPs) are widespread among higher plants of different taxonomic orders. In this study, we report on the RIP sequences found in the genome/transcriptome of several important Rosaceae species, including many economically important edible fruits such as apple, pear, peach, apricot, and strawberry. All RIP domains from Rosaceae share high sequence similarity with con...

We evaluated the role of the humoral arm of the immune response in causing or contributing to virus-induced diabetes. Transgenic mice expressing the nucleoprotein (NP) or glycoprotein (GP) of the lymphocytic choriomeningitis virus (LCMV) under control of the rat insulin promoter (RIP) in pancreatic beta cells (RIP-LCMV) and RIP-LCMV mice with genetic dysfunction of B cells (RIP-LCMV x microMT/m...

The expicit restricted isometry property (RIP) measurement matrices are needed in practical application of compressed sensing in signal processing. RIP matrices from Reed-Solomon codes, BCH codes, orthogonal codes, expander graphs have been proposed and analysised. On the other hand binary constant weight codes have been studied for many years and many optimal or near-optimal small weight and d...

The technological objectives of this project are to investigate the mechanics of wave-driven flow on complex topographies. Specifically, we are examining the occurrence, forms, and detailed causes of flow instabilities over complex topographies; the influence of three dimensional topographical features on large scale flow features, the forms and utility of simplified expressions in predicting f...

ALVAREZ-ELLACURIA, A.; ORFILA, A.; OLABARRIETA, M.; MEDINA, R.; VIZOSO, G., and TINTORÉ, J., 2010. A nearshore wave and current operational forecasting system. Journal of Coastal Research, 26(3), 503–509. West Palm Beach (Florida), ISSN 0749-0208. An operational forecasting system for nearshore waves and wave-induced currents is presented. The forecasting system (FS) has been built to provide r...

Field experiments in the surfzone were conducted on a meso-tidal beach stretch between Sinquerim and Baga off Goa India's central west coast. Surfzone waves currents measured using an array of seabird wave tide gauges Aanderaa RCM9 current meters. Rip observed prominently this with increased intensity during ebb tide. Six longshore prediction equations are tested for their suitability region. T...

Plant RNA editing modifies cytidines (C) to uridines (U) at specific sites in the transcripts of both mitochondria and plastids. Specific targeting of particular Cs is achieved by pentatricopeptide proteins that recognize cis elements upstream of the C that is edited. Members of the RNA-editing factor interacting protein (RIP) family in Arabidopsis have recently been shown to be essential compo...