Levels of some serum metabolites were studied in wistar strain rats raised on diets deficient in magnesium (mg) and/or riboflavin (Rb). Though growth was suppressed in the rats fed the vitamin deficient (+MgRb) and magnesium deficient (-Mg +Rb) diets, it was more retarded in those fed the double deficient diets (-Mg -Rb) when compared with the control (P<0.01; +Mg+Rb). Significant decreased lev...

Objective: To investigate the impact of fortification by comparing food records and selected biochemical indicators of nutritional status preand post-fortification. Design: Mean intake from 24 h recalls (n 142) was compared with the Estimated Average Requirement (EAR) to determine the proportion with inadequate intake. In a subsample (n 34), diet and serum retinol, folate, ferritin and Zn were ...

on a weight basis to those used clinically has significant effects upon riboflavin metabolism in the animal as a whole: (a) the activity coefficient of erythrocyte glutathione reductase, an FAD-containing enzyme used as an index of riboflavin status physiologically, was elevated, a finding compatible with a deficiency state, (b) the urinary excretion of riboflavin was more than twice that of ag...

Vascularization of the cornea of the rat in the absence of antecedent pathology is probably a specific and the most reliable criterion of riboflavin deficiency. Its initiation and repair may be used for testing the biological activity of compounds structurally related to riboflavin. The facts that the invading capillaries are easily visible in the living animal and that the growth and regressio...

A multifaceted analysis of the nutritional status of 196 subjects, aged over 65, institutionalized in hospitals, residential accomodation, and sheltered dwellings and of noninstituionalized subjects was untaken. Subjects of hospital and home, with or without multivitamin supplementation, were grouped separately. The study comprised of 3-day weighed dietary record, biochemical determinations, an...