We are studying endoplasmic reticulum-associated degradation (ERAD) with the use of a truncated variant of the type I ER transmembrane glycoprotein ribophorin I (RI). The mutant protein, RI(332), containing only the N-terminal 332 amino acids of the luminal domain of RI, has been shown to interact with calnexin and to be a substrate for the ubiquitin-proteasome pathway. When RI(332) was express...

PURPOSE The aim of this retrospective study was to assess the utility of a voxel-based analysis (VBA) method for (201)Tl SPECT in glioma, compared to conventional ROI analysis. METHODS We recruited 24 patients with glioma (high-grade 15; low-grade 9), for whom pre-operative (201)Tl SPECT and MRI were performed. SPECT images were coregistered with MRI. The uptake ratio (UR) images of tumor to ...

We investigated the cardioprotective effect of renal ischemic postconditioning (RI-PostC) and its mechanisms in a rabbit model. Rabbits underwent 60 min of left anterior descending coronary artery occlusion (LADO) and 6 h of reperfusion. The ischemia-reperfusion (IR) group underwent LADO and reperfusion only. In the RI-PostC group, the left renal artery underwent 3 cycles of occlusion for 30 se...

The refractive index (RI) is a fundamental parameter of materials that can be used to distinguish and sort materials of different nature. Although the RI of a virus is required for many optics-based biosensing applications, RIs of animal viruses have never been measured. Here we have developed a technique that can measure the RI of individual viruses in aqueous media with high precision. This t...

OBJECTIVE To evaluate the validity of resistive index (RI) in conjunction to the morphological appearances. METHODS Prospective cross sectional survey of 37 females with adnexal masses was selected through non probability sampling admitted in Obstetrics units, in a private hosital from January 2009 to March 2010. All women underwent transabdominal and transvaginal ultrasound and ovarian masse...

INTRODUCTION Residual inhibition (RI) is the temporary inhibition of tinnitus by use of masking stimuli when the device is turned off. OBJECTIVE The main aim of this study was to evaluate the effects of RI induced by auditory electrical stimulation (AES) in the primary auditory pathways using early auditory-evoked potentials (AEPs) in subjective idiopathic tinnitus (SIT) subjects. MATERIALS...