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background: the prevalence of toxoplasma gondii infection in the blood donors has been poorly studied. the aim of this study was to assess the prevalence of acute and chronic toxoplasmosis in blood products. methods: a total of 250 blood products (112 fresh frozen plasma and 138 packed cells) in the blood transfusion institute, shiraz, iran were tested for spe-cific t. gondii antibodies (igg an...

h.pylori infection stimulates immune responses. these responses at the mucosal level are predominantly of iga types, while circulating antibodies against this microorganism are predominantly igg classes. igm antibodies are rarely found and seem to be non-specific for this bacterium. in this research, water extract antigen, from three strains of h.pylori (isolated from patients with gastritis, d...

background and objectives : hepatitis c virus genotyping appears to be vital for predicting the response to antiviral therapy. the present study aimed to analyze the hcv genotypes in relation to persistence or clearance of the virus in residents of hamadan province, west-iran. material and methods : a total of 1159 recorded questionnaires of hcv infected people were evaluated in this prospectiv...

since the incidence of symptomatic congenital cytomegalovirus infection is low (~0.05%) and risk factors are not well defined, it is difficult to develop strategies for prevention. the aim of this study was to recognise the utility of specific immunoglobulin g avidity analysis for distinguishing primary infection from past/recurrent infection. sera from 50 women with cytomegalovirus specific im...

background and aims. lichen planus is a relatively common chronic mucocutaneaous disease with an unknown cause, and is considered a manifestation of cell-mediated immune response. hepatitis c virus (hcv) and its subgroups have been associated with lichen planus in different geographic locations. the present study was undertaken to evaluate the prevalence of hcv antibody in patients with lichen ...

background: toxoplasmosis is a world wide parasitic disease infecting human by oocyst, tissue cyst or tachyzoites in raw meat, water or congenitally during pregnancy. toxoplasmosis can cause abortion in pregnant women. the current seroepidemiological study was designed to assess toxoplasmosis in pregnant women with or without the history of abortion. methods: in a case–control study the antibod...

alpha-fetoprotein (afp), a serum glycoprotein belonging to the onco-developmental proteins group, serves as a marker both in cancer research and in studies concerning fetal development and fetal pathophysiology. monoclonal anti-afp antibodies are essential reagents in developing appropriate techniques for measurement of this protein. in this study, in order to produce anti-afp monoclonal antibo...

to evaluate the correlation of cytomegalovirus (cmv) and coronary artery disease (cad), one-hundred patients with cad and the same number of healthy individuals as a control group were randomly selected and studied for anti-cmv using elisa method. ninety percent of patients and 77 percent of the control group were anti-cmv positive and statistical analysis showed a significant correlation betwe...