نتایج جستجو برای: rhg csf

تعداد نتایج: 28517  

2015
Shuqi Jiang Xianrong Shen Yuming Liu Ying He Dingwen Jiang Wei Chen

This study investigated the radioprotective effect of Sipunculus nudus L. polysaccharide (SNP) in combination with WR-2721, rhIL-11 and rhG-CSF on irradiated mice. A total of 70 Imprinting Control Region (ICR) mice were divided into seven groups: the control group, the model group and five administration groups. All groups, except the control group, were exposed to a 5 Gy (60)Co γ-ray beam. Blo...

Journal: :Blood 1995
A Bacigalupo G Broccia G Corda W Arcese M Carotenuto A Gallamini F Locatelli P G Mori P Saracco G Todeschini

Patients with severe aplastic anemia (SAA) and a neutrophil (PMN) count of less than 0.5 x 10(9)/L are exposed to a high risk of early mortality when treated with antilymphocyte globulin (ALG) and steroids, with the major problem being infectious complications. The addition of human recombinant granulocyte colony-stimulating factor (rhG-CSF) to ALG may reduce early mortality by improving neutro...

Journal: :Blood 1998
K Shibuya H Akahori K Takahashi E Tahara T Kato H Miyazaki

Previous studies have shown that daily multiple administration of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) markedly stimulates thrombopoiesis and effectively ameliorates thrombocytopenia, and in most cases anemia and neutropenia, in myelosuppressed animals. In this study, we evaluated the effects of a single intravenous injection of PEG-rHuMGDF on he...

A.R Saeedinia B Akbari M J Fallah, M Karimi M Soleimani M Vaez M Zeinoddini N Maghsoudi

Bakground: Granulocyte colony-stimulating factor (G-CSF) is a cytokine that stimulates hematopoiesis and induces proliferation and differentiation of granulocyte progenitor cells as well as production of bone marrow neutrophilic granulocyte colonies.  Nowadays, human recombinant G-CSF(hr G-CSF)is used for the treatment of chemotherapy- and radiotherapy-induced neutropenia, and also in patients ...

Journal: :Blood 1991
T Pietsch C Bührer K Mempel T Menzel U Steffens C Schrader F Santos C Zeidler K Welte

Severe congenital neutropenia (SCN) is a disorder of myelopoiesis characterized by severe neutropenia or absence of blood neutrophils secondary to a maturational arrest at the level of promyelocytes. We examined peripheral blood mononuclear cells (PBMC) of SCN patients who demonstrated normalization of their blood neutrophil counts in a phase II clinical study with recombinant human granulocyte...

Journal: :Bone marrow transplantation 1995
I Langenmayer C Weaver C D Buckner K Lilleby F R Appelbaum K Longin S Rowley R Storb J Singer W I Bensinger

Forty six patients with lymphoid malignancies receiving autologous transplants using three different sources of hematopoietic stem cells were compared for engraftment parameters. Thirteen patients (five with multiple myeloma, seven with non-Hodgkin's lymphoma and one with Hodgkin's lymphoma) received autologous marrow with post-transplant growth factors (group 1). During the same time interval,...

Journal: :Blood 1991
K Yong H Cohen A Khwaja H M Jones D C Linch

The hematopoietic growth factors, granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF), enhance the effector functions of mature myeloid cells, including the interaction with vascular endothelium. We examined the direct effect of recombinant human GM-CSF (rhGM-CSF) and recombinant human G-CSF (rhG-CSF) on the growth and function of cultured...

Journal: :iranian journal of medical sciences 0
m j fallah department of genetic engineering, research center for science and biotechnology, tehran, iran b akbari department of genetic engineering, research center for science and biotechnology, tehran, iran a.r saeedinia department of genetic engineering, research center for science and biotechnology, tehran, iran m karimi department of biotechnology, pasteur institute of iran, tehran, iran m vaez department of genetic engineering, research center for science and biotechnology, tehran, iran m zeinoddini department of genetic engineering, research center for science and biotechnology, tehran, iran

bakground: granulocyte colony-stimulating factor (g-csf) is a cytokine that stimulates hematopoiesis and induces proliferation and differentiation of granulocyte progenitor cells as well as production of bone marrow neutrophilic granulocyte colonies.  nowadays, human recombinant g-csf(hr g-csf) is used for the treatment of chemotherapy- and radiotherapy-induced neutropenia, and also in patients...

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