The concurrence of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) has been reported infrequently. Eleven patients are described here with both RA and SLE, in whom the diagnoses were separated by one to 24 years. Because of the difficulty in diagnosing RA occurring subsequent to SLE, only patients with classical RA as their initial diagnosis were included. Further difficulties ...

Subcutaneous nodules which are characterised by central fibrinoid necrosis, surrounded by histiocytes and fibroblasts are traditionally considered to be manifestations of rheumatoid arthritis or rheumatic fever. In recent years, however, cases in which such nodules appeared in otherwise healthy children have been reported. Beatty (1959) reported nine children, aged between eleven days and nine ...

A WEALTH of literature has sprung up, particularly in the last few years, dealing with subcutaneous nodule formation in acute rheumatism and rheumatoid arthritis, but there is still much difference of opinion as to whether the two are closely related or whether the tissue changes are non-specific and unrelated aetiologically. As Keil (1938) writes, in a very full and comprehensive analysis of t...

BACKGROUND Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease, wherein late diagnosis and treatment leads to deformities and disability. OBJECTIVE The aim of the study was to assess and describe the clinical and immunological characteristics, activity status of the disease, and functional capacity in a cohort of Ecuadorian patients with RA. METHODS This is a cross-secti...

The literature on nodule formation in rheumatic disease is confused by the absence of co-ordination of clinical data and pathological material. Nodules of one sort or another are found in many rheumatic syndromes, and also in conditions which are barely within the scope of that designation. Parkes Weber (1943) classified nodules into eight types: those occurring in acute rheumatism, rheumatoid ...

Introduction Rheumatoid arthritis is a systemic inflammatory disorder that most commonly affects the joints, causing progressive, symmetric, erosive destruction of cartilage and bone, which is usually associated with autoantibody production. Rheumatoid arthritis affects ∼1% of the population in developed countries. The incidence and prevalence of rheumatoid arthritis in developing countries is ...

A 72 year old male patient, with rheumatoid arthritis of 20 years duration presented to us in 2009 with weight loss of 3 kg and no respiratory symptoms. Additional features included a history of empyema nineteen years back treated as tuberculosis (old chest radiographs not available). He also had history of subcutaneous rheumatoid nodules. He had been taking methotrexate and leflunomide for man...