Section on Quantitative Imaging and Tissue Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA, Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA, Quantitative Medical Imaging Section, National Institute of Biomedical Im...

BACKGROUND The purpose of this study was to investigate the role of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) as a prognostic marker in conventional papillary thyroid carcinoma (PTC). METHODS A total of 397 patients who underwent ultrasound-guided fine-needle aspiration biopsy (FNAB) and surgery for conventional PTCs were enrolled. The association between the Bethesda ca...

Introducción y objetivo: La medicina Nuclear, desde sus inicios, ha tenido un papel importante en el estudio tratamiento de la patología tiroidea. El hallazgo nódulo tiroideo es una situación muy frecuente práctica clínica diaria. En actualidad, desarrollo nuevas técnicas como son ecografía alta resolución punción por aspiración con aguja fina originado avance diagnóstico manejo ésta patología....

Zhuo Zhang, Meili Zhang, Kayhan Garmestani, Vladimir S. Talanov, Paul S. Plascjak, Barbara Beck, Carolyn Goldman, Martin W. Brechbiel and Thomas A. Waldmann Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bet...

1Cancer Prevention and Control Division, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; 2Contractor to the National Cancer Institute (NCI), Bethesda, MD; 3Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley; 4Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston; 5Cancer Therapy Evaluation Prog...

1National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), Bethesda, MD; 2Department of Medicine, Duke University Medical Center, Durham, NC; 3Office of Research Services, Division of Veterinary Resources, 4National Eye Institute, and 5National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, MD; 6Medical Service, Durham Veterans Affairs Medical Cent...

Specimen Adequacy TBS 1991 reported the adequacy of cervical cytology preparations in three categories: “satisfactory,”“unsatisfactory,”and “satisfactory but limited by,” or SBLB. SBLB included factors such as the lack of transformation zone components and the presence of partially obscuring factors (i.e., blood or inflammation). This category was confusing to some clinicians and prompted unnec...

OBJECTIVE Several molecular marker tests are available to refine the diagnosis of thyroid nodules. Knowing the true prevalence of malignancy (PoM) within each cytological category is considered necessary to select the most appropriate test and to interpret results accurately. We describe our institutional PoM among cytological categories and report our experience with molecular markers. DESIG...

INTRODUCTION Thyroid swelling is common problem among South Asian women. Although benign nodules far outnumber cancerous lesions, the risk of malignancy needs to be evaluated preoperatively for which fine needle aspiration cytology (FNAC) is widely used. Bethesda system for reporting thyroid cytopathology (BSRTC) was introduced to streamline the reporting of thyroid aspirates. We aimed to evalu...