Canine degenerative myelopathy (DM) is characterized by progressive degeneration of the spinal cord. Although atrophic changes in the intercostal muscles were previously reported in the late stage of DM in Pembroke Welsh Corgis (PWCs), changes in respiratory function have not yet been examined. In the present study, we performed an arterial blood gas analysis and measured respiratory movements ...

Three patients are described who illustrate distinctive patterns of sleep-disordered breathing that we have observed in patients who are receiving long-term, sustained-release opioid medications. Polysomnography shows respiratory disturbances occur predominantly during non-rapid eye movement (NREM) sleep and are characterized by ataxic breathing, central apneas, sustained hypoxemia, and unusual...

BACKGROUND Whether loss of wakefulness itself can influence pharyngeal dilator muscle activity and responsiveness is currently unknown. A study was therefore undertaken to assess the isolated impact of sleep on upper airway muscle activity after minimising respiratory/mechanical inputs. METHODS Ten healthy subjects were studied. Genioglossus (GG), tensor palatini (TP) and diaphragm (DIA) elec...

Mechanical ventilation of cats in sleep and wakefulness causes apnea, often within two to three cycles of the ventilator. We recorded 137 medullary respiratory neurons in four adult cats during eupnea and during apnea caused by mechanical ventilation. We hypothesized that the residual activity of respiratory neurons during apnea might reveal its cause(s). The results showed that residual activi...

the recently emerged middle east respiratory syndrome coronavirus (mers-cov) emerged in the middle east region in 2012. the virus is phylogenetically related to bat cov, but other animal species like camels and goats may potentially act as an intermediate host by spreading the virus to humans. this virus is thought to cause a severe disease in patients with underlying comorbidities. laboratory ...

respiratory syncytial virus (rsv) is the major cause of lower respiratory tract infections in infants,and also an important factor for hospitalization during the winter months. to determine the prevalence and importance of rsv as a cause of acute lower respiratory tract infection, we carried out a prospective study during 5 months period from november to march 1998 in 6 pediatric hospitals. a n...

Our group is currently developing an intravenous respiratory assist device that uses a centrally located pulsatile balloon within a hollow fiber bundle to enhance gas exchange rate via active mixing mechanism. We tested the hypothesis that the non-symmetric inflation and deflation of the balloon lead to both nonuniform balloon-generated secondary flow and nonuniform gas exchange rate in the fib...

Background: Whether loss of wakefulness itself can influence pharyngeal dilator muscle activity and responsiveness is currently unknown. A study was therefore undertaken to assess the isolated impact of sleep on upper airway muscle activity after minimising respiratory/mechanical inputs. Methods: Ten healthy subjects were studied. Genioglossus (GG), tensor palatini (TP) and diaphragm (DIA) elec...

The effects of selected metabolic and respiratory inhibitors on the gliding motility of Flexibacter polymorphus were examined. Motility and oxygen consumption were quantitatively inhibited in a reversible manner by specific respiratory poisons, suggesting that gliding velocity was linked to electron transport activity. Arsenate had little influence on the number or rate of gliding filaments, de...