Computational Biology has increasingly become an important tool for biomedical and translational research. In particular, when generating novel hypothesis despite fundamental uncertainties in data and mechanistic understanding of biological processes underpinning diseases. While in the present book, we have reviewed the necessary background and existing novel methodologies that set the basis fo...

In this article, we offer a broadened view of service innovation—one grounded in service-dominant logic—that transcends the tangible–intangible and producer–consumer divides that have plagued extant research in this area. Such a broadened conceptualization of service innovation emphasizes (1) innovation as a collaborative process occurring in an actor-to-actor (A2A) network, (2) service as the ...

An explosive increase of urban population, practically in all major cities and towns, has the consequent strain on the existing system manifested in an environmental chaos. The phenomena of accelerated urbanisation is the main culprit, wherein besides bringing higher standard of living, it has also brought problems, as growth of dense and unplanned residential areas, environmental pollution, no...

Formal modelling techniques that employ principles of finite state automata have been increasingly used for shop-floor control. These approaches have focused primarily on unmanned systems where the self-contained logic for control of the systems is embedded within the model(s). To date, human operators are seldom configured within the modelling detail required for these systems. The result has ...

BACKGROUND Medical students face an information-rich environment in which retrieval and appraisal strategies are increasingly important. OBJECTIVE To describe medical students' current pattern of health information resource use and characterize their experience of instruction on information search and appraisal. METHODS We conducted a cross-sectional web-based survey of students registered ...

Improved economic, social and environmental decision–making are principal objectives for investing in the development of spatial data infrastructure (SDI) at all political and administrative levels. So much so, resolution 7 of the recent 5 Global Spatial Data Infrastructure (GSDI) conference in Cartagena, Colombia argued that the purpose of the GSDI is to improve the availability, accessibility...

1567-4223/$ see front matter 2011 Elsevier B.V. A doi:10.1016/j.elerap.2011.10.001 ⇑ Corresponding author. Tel.: +886 2 2939 3091x85 E-mail addresses: [email protected] (C.-C. (J.-S. Chiou). This study applies social capital theory to investigate how a player’s network centrality in an online gaming community (i.e., a guild) affects his/her attitude and continuance intention toward a Massi...

Scheduling and resource allocation problems are pervasive and important in the management of industrial and government organizations. With advent of new technology and fast evolvement in industry, the enterprise is gradually moving toward global manufacturing for efficient operational management and competent strategic decision making. In the past two decades, researchers and practitioners have...

Chromatin immunoprecipitation, DNase I hypersensitivity and transposase-accessibility assays combined with high-throughput sequencing enable the genome-wide study of chromatin dynamics, transcription factor binding and gene regulation. Although rapidly accumulating publicly available ChIP-seq, DNase-seq and ATAC-seq data are a valuable resource for the systematic investigation of gene regulatio...

Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. However, the effective and efficient use of biobank resources depends on their accessibility. In fact, making bio-resources promptly accessible to everybody may increase the benefits for society. Furthermore, optimizing their use and ensuring their quality will pr...