Objectives:Staphylococcus aureus infections in burn patients can lead to serious complications and death. The frequency of S. aureus infection is high in low- and middle-income countries presumably due to limited resources, misuse of antibiotics and poor infection control. The objective of the present study was to apply population genomics to precisely define, for the first time, the transmissi...

Staphylococcus aureus and Staphylococcus epidermidis strains isolated at eight large medical centers in Korea were examined for methicillin resistance and resistance to eight other antibiotics; cefazolin, cefamandole, cefuroxime, cefoxitin, cefotaxime, moxalactam, penicillin G and vancomycin. Methicillin resistance was found in 296 of 1225 strains (24.2%) of S. aureus and 126 of 348 strains (36...

The purpose of this project is to study the evolution of the bacteria, meticillin-resistant staphylococcus aureus (MRSA). We will study and evaluate a few of the genes and mutations of MRSA that enable it to be resistant to many antibiotics and antimicrobial agents. Visual and image processing will be used to create data charts, graphs and plots to better conceive the results of the research. I...

MUT056399 is a highly potent new inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli. In vitro, MUT056399 was very active against S. aureus strains, including methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. aureus (MRSA), linezolid-resistant, and multidrug-resistant strains, with MIC(90)s between 0.03 and 0.12 μg/ml. MUT056399 was also active again...

ST239-MRSA-SCCmec III (ST239, sequence type 239; MRSA, methicillin-resistant Staphylococcus aureus; SCCmec III, staphylococcal cassette chromosome mec type III) is the most predominant clone of hospital-acquired methicillin-resistant S. aureus in mainland China. We report here the complete genome sequence of XN108, the first vancomycin-intermediate S. aureus strain isolated from a steam-burned ...

Background: Nosocomial infections are an important cause of hospital mortalities. Staphylococcus aureus (S. aureus) carriers among medical staff are an important source of nosocomial infections. The purpose of this study was to investigate the prevalence of the nasal carriers of S. aureus and antibiotic resistance in staff of Nikuee Hospital, Qom, Iran. Materials and Methods: In this cross-s...

The presence, distribution and antibiotic profile of staphylococci was determined in River Ganga in Uttarakhand region (India). A total of 128 staphylococcal strains were obtained from 32 sites which corresponded to three species namely S. aureus, S. hominis and S. aegilis. S. aureus dominated the staphylococcal population comprising of 68.75% of the total staphylococci. The sensitivity of stap...

conclusions our findings should raise awareness about the role of sea and sec enterotoxins, in resistant strains of s. aureus, as a risk factor for ms exacerbation. it is better to keep ms patients away from polluted environments of hospitals and health centers. objectives the present study was carried out to investigate the role of resistant strains of enterotoxigenic s. aureus in ms exacerbat...

BACKGROUND Fluoroquinolones are broad-spectrum antibiotics widely used in the treatment of bacterial infections such as Staphylococcus aureus isolates. Resistance to these antibiotics is increasing. MATERIAL/METHODS The occurrence of mutations in the grlA and gyrA loci were evaluated in 69 fluoroquinolone-resistant S. aureus isolates from 2 teaching hospitals of Tehran University of Medical S...