Although there is extensive evidence for impaired endocrine function in fishes exposed to environmental chemicals, information is currently lacking on reproductive endocrine effects of other environmental stressors such as hypoxia. The effects of ten weeks exposure to low dissolved oxygen (DO: 2.7 ppm and 1.7 ppm) on reproductive morphometric and endocrine responses in female Atlantic croaker (...

Human chorionic gonadotropin (hCG) was initially thought to be made only during pregnancy, but is now known to also be synthesized by a variety of cancers and is associated with poor patient prognosis. Transgenic expression of βhCG in mice causes hyper-luteinized ovaries, a loss in estrous cyclicity and infertility, increased body weight, prolactinomas and mammary gland tumors. Strategies were ...

Background Infertility as the bitterest life experience can affect sexual function. Also, infertility is a reproductive health problem. Many studies showed that agitation, stress, depression, marital dissatisfaction and sexual dysfunction are psychological outcomes resulted from infertility. There are many factors influencing the female sexual function, one of them is body mass index. The prese...

Male factor infertility often happened in patients with varicocele and genetic disorder. Microsurgical varicocele is the most effective and safe treatment option for male infertility in patients with varicocele. Y chromosome microdeletions and chromosomal abnormalities are the two types of genetic disorder. Now we could use commercial detection kits through PCR amplification of selected regions...

The objectives: to assess the spectrum and diagnostic value of antiphospholipid antibodies (APLA) by placental dysfunction. Materials methods. A study APLA in 122 patients with dysfunction II III trimesters pregnancy was carried out. control group included 64 practically healthy women a physiological course gestation without complicated reproductive somatic history. Results. overall frequency d...

Epidemiological studies demonstrate a relationship between pathological events during foetal development and future cardiovascular risk and the term 'foetal programming of cardiovascular disease' has been coined to describe this phenomenon. The use of assisted reproductive technologies (ARTs) is growing exponentially and 2-5% of children are now born by this procedure. Emerging evidence indicat...

Background Nonyl phenol (NP) has been considered an endocrine disrupting substance causing reproductive dysfunction and increase in reactive oxygen species production in different organs including testis. vitamin E (VitE) is a potent scavenger of free radicals and is able to prevent the membrane damage mediated by free radicals The aim of this study was to elucidate the protective effects of Vi...

The article provides an overview of scientific information on modern approaches to reproductive health protection, innovative methods for early detection disorders and timely correction reduced capabilities the body, including infertility. main physiological factors are genetic predisposition, mitochondrial dysfunctions, genomic instability, oxidative stress, etc. In particular, mitochondria ma...

The subjective experience of stress leads to reproductive dysfunction in many species, including rodents and humans. Stress effects on reproduction result from multilevel interactions between the hormonal stress response system, i.e., the hypothalamic-pituitary-adrenal (HPA) axis, and the hormonal reproductive system, i.e., the hypothalamic-pituitary-gonadal (HPG) axis. A novel negative regulat...

As man-made chemicals (anthropogenic) are increasing in number and amount of use, it is not uncommon for farmers, ranchers, consultants, or veterinarians to suspect a xenobiotic (strange or foreign substance) as the cause of reproductive failures. In this article, the authors discuss toxicants that have been shown to affect reproduction, with emphasis on food-producing animals and fowl. The dis...