In eukaryotic cells, DNA replication starts at many origins in each chromosome during S phase of cell cycle. Each origin is activated at different time points in S phase, which takes place once and only once per cell cycle. In yeast and most likely higher eukaryotes, the origin-recognition complex (ORC) and several other initiation factors play a pivotal role in activation and regulation of rep...

As part of a metazoan parasite survey of elasmobranchs from Malaysian Borneo, specimens of Rhoptrobothrium Shipley et Hornell, 1906 were collected from the eagle rays Aetomylaeus maculatus (Gray) and Aetomylaeus niehofii (Bloch et Schneider). The type species is redescribed from its type host, and a neotype specimen is designated. In addition, three new species of Rhoptrobothrium are described:...

Twins have always attracted attentionÐ Romulus and Remus, Castor and Pollux, Jacob and Esau, Fafner and Fasold; there has always been intrigue, mystery and confusion surrounding two-in-one and one-in-two. The interest for Laterality and lateralisation is compounded, because if it is the difference between an individual’ s two sides that results in laterality, how are those two sides represented...

Modeling is a key task in order to analyze, understand, and improve business processes and organizational structures, and to support the design, implementation, and management of information and communication technologies in general and knowledge management systems (KMSs) in particular. Process-oriented knowledge management (Maier, 2004; Maier & Remus, 2003) is a promising approach to provide t...

In this study, a total of nine different biotransformation products of the Fusarium mycotoxin deoxynivalenol (DON) formed in wheat during detoxification of the toxin are characterized by liquid chromatography-high resolution mass spectrometry (LC-HRMS). The detected metabolites suggest that DON is conjugated to endogenous metabolites via two major metabolism routes, namely 1) glucosylation (DON...

Due to the receding sea-ice extent in the Arctic, and the potentially large undiscovered petroleum resources present north of the Arctic circle, offshore activities in ice-infested waters are increasing. Due to the presence of drifting sea-ice and icebergs, ice management (IM) becomes an important part of the offshore operation, and an important part of an IM system is the ability to reliably m...

Twins have occupied a prominent place in human imagination and mythology since ancient times. Greek mythology enshrined the twins Castor and Pollux in the heavens as the two stars of the constellation Gemini. Ancient Rome was said to have been founded by twins, Romulus and Remus, raised in the wild by a wolf. The establishment of several North American Indian tribes, such as the Hurons and Iroq...

ABSTRACT: Bacteriophages have been investigated as alternative to the treatment of bacterial infections, including bovine mastitis, in production animals. In this meta-analysis, we evaluated vitro efficiency phages Staphylococcus aureus against S. aureus, which is involved etiology mastitis. Seventeen studies were included and lytic activity was extracted using proportion analysis. The obtained...