The drug release pattern from an orally administrated pharmaceutical dosage form can be significantly affected by simultaneous food intake and drug administration due to the changes in the gastrointestinal physiology, in particular because of the pH profile evolution and of the mixing conditions. In this work, the release from a commercial diclofenac tablet subjected to the pH conditions experi...

This paper proposes two alternative schemes for the online recognition of control chart patterns (CCPs), namely: 1 a scheme based on direct continuous recognition 2 a scheme based on ‘recognition only when necessary’. The study focuses on recognition of six CCPs plotted on the Shewhart X-bar chart, namely, random, shift-up, shift down, trend-up, trend-down and cyclic. The artificial neural netw...

In this study, a system of dexamethasone sodium phosphate (DEXP)-loaded chitosan nanoparticles embedded in poly-ε-caprolacton (PCL) and gelatin electrospun nanofiber scaffold was introduced with potential therapeutic application for treatment of the nervous system. Besides anti-inflammatory properties, DEXP act through its glucocorticoid receptors, which are involved in the inhibition of astroc...

Microencapsulation of liquid orange oil as a common flavoring agent in food industries by complex coacervation in a gelatin – gum arabic polymeric wall system was studied. At a fixed ratio of 10% w/v as concentration of the materials used in this study, trend of changes of microencapsulation process variables using different wall polymeric contents along with varying levels of the core to wall ...

We present a methodology that detects spatial patterns of 3-dimensional point processes that include a mass within the study region. Spatial patterns such as clustering, randomness, or repulsion are considered in respect to the mass surface. Our method closely resembles Ripley’s K Function but is modified to discern the pattern about the mass surface. We walk though the definition and derivatio...

The Kaantabay sa Kauswagan (or Partners in Development) Program is a social amelioration program primarily designed to empower squatters and slum dwellers which comprise some 25 percent of the city population residing in 21 urban barangays of Naga City. So far, it has resettled 2,017 families to relocation sites with a combined area of 33 hectares; secured homelots for 789 squatter families; an...

Better understanding of the role of learning in technical progress is important for the development of innovation theory and technology policy. This paper presents a comparative analysis of the effect of learning and technical change in electricity generation technologies. We use simultaneous two-factor learning and diffusion models to estimate the effect of learning by doing and learning by re...

This study evaluated brain natriuretic peptide (BNP) release in acute myocardial infarction (AMI), absolute values as well as pattern of its release. There are two different patterns of BNP release in AMI; monophasic pattern--concentration in the first measurement is higher than in the second one, and biphasic pattern--concentration in the first measurement is lower than in the second one. We o...

In the present study, a nanoporous metal organic framework (MOF) based on iron metal and amino terephthalate ligand MIL-101-NH2-Fe has been used as a carrier for loading and in vitro release of 5-flurouracil (5-FU) anticancer drug. The 5-FU drug loaded MOF was 13 wt % by using thermogravimetric analysis (TGA). The 5-FU release was monitored under physiological condition at 37°C, pH 7.4 in simul...