background and purpose: leukemia is the most prevalent type of cancer in children and its prognostic factors vary in different geographic locations. the aim of this study was to estimate the 5 years survival rate of children suffering from leukemia in kerman, iran and to investigate the factors which might influence it. materials and methods: this was a cohort study conducted on patients with a...

OBJECTIVES To evaluate the efficacy of a fixed dose of radioactive iodine (131-I) in the treatment of thyrotoxicosis, and to identify risk factors associated with treatment failure. DESIGN Retrospective study. SETTING Thyroid Clinic of a regional hospital in Hong Kong. PATIENTS Patients receiving their first dose of radioactive iodine for the treatment of thyrotoxicosis during the inclusi...

Retrospective analysis of 119 endoscopically proven cases of duodenal ulcer, treated with Famotidin (40 mg),Cimetidine (800 mg) and Ranitidine (300 mg) at bed -time, showed heating rates of 91, 74 and 68%, respectively, at 6 weeks. Twenty patients were followed up for one year on maintenance dose and endoscoped at 3, 6 and 12 months. Despite taking the drug regularly a relapse rate of 14% was s...

STUDY OBJECTIVES To determine the incidence and risk factors of relapse after an emergency department (ED) visit for COPD exacerbation. DESIGN Prospective cohort study as part of the Multicenter Airway Research Collaboration. SETTING Twenty-nine North American EDs. PATIENTS ED patients with COPD exacerbations, age > or =55 years. For the present analysis of post-ED relapse, the cohort was...

BACKGROUND AND OBJECTIVES Coagulase-negative Staphylococcus species is the most common cause of peritoneal dialysis-related peritonitis; however, the optimal treatment strategy of coagulase-negative Staphylococcus species peritonitis remains controversial. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS All of the coagulase-negative Staphylococcus species peritonitis in a dialysis unit from 199...

Objective] To evaluate the relapse rate after treatment of a twice weekly intermittent chemotherapy during continuation phase in the patients with pulmonary tuberculosis in two years poriod after completion of chemotherapy. [Methods] The patients with drug susceptible pulmonary tuberculosis treated with 2HRZE/4H2R2 under the supervision by the pharmacists or the patients treated with 2HRZE/4HR ...

Although 2-chlorodeoxyadenosine (2-CdA) is effective in inducing complete remissions (CRs) in the majority of patients with hairy cell leukemia (HCL), neither the actual relapse rate, the clinical factors that may predict relapse, the longterm outcome, nor the response rate to re-treatment at relapse has been clearly determined. Fifty-two consecutive patients with previously untreated or treate...

BACKGROUND We examined efficacy, toxicity, relapse, cost, and quality-of-life thresholds of hypothetical HIV cure interventions that would make them cost-effective compared to life-long antiretroviral therapy (ART). METHODS We used a computer simulation model to assess three HIV cure strategies: Gene Therapy, Chemotherapy, and Stem Cell Transplantation (SCT), each compared to ART. Efficacy an...

BACKGROUND Recent studies have demonstrated the overexpression of cyclooxygenase-2 (COX-2) in endometriosis. The aim of this study was to investigate the correlation between COX-2 expression and the clinical outcome rate in a homogeneous series of patients undergoing fertility-sparing complete laparoscopic ablation for severe endometriosis. METHODS COX-2 expression was analysed by immunohisto...