Uterine artery embolization (UAE) research has largely been focused on women over 40 years, yet women of reproductive age undergo UAE without any increased morbidity. Some physicians refrain from recommending UAE to women in this age group because of some research findings showing a negative effect on fertility. This review presents a comprehensive discussion of the fertility potential of women...

We examine Phase I cancer clinical trial designs that use toxicity estimates based on all available data at each dose-allocation decision, but refrain from employing parametric models or Bayesian decision rules. We show that one such design family, called here “interval designs”, converges almost surely to the maximum tolerated dose under fairly general conditions. Another family called “point ...

We investigated the production of collaborative annotations of maps with mobile devices, looking for the reasons why people might want to produce these notes and how they might do so. We conducted a field trial with 21 participants over 3 months in the center of Geneva, Switzerland. We collected fewer messages than expected and we attributed the reasons for this result with a lack of social con...

The current popularity of methadone maintenance treatment appears justified largely on the strength of outcome studies which demonstrate its general effectiveness in facilitating the social rehabilitation of heroin addicts. Gearing (1971), for example, reports that only one percent of patients remaining in treatment revert to heroin use, that 80 to 90 percent remain free of other serious drug a...

Every individual is influenced by his personal experiences and background. This means that we each bring to our everyday interactions with others our biases, religious beliefs, and even our political agendas. While most physicians do an excellent job of focusing on patients and leaving personal opinion and biases aside, this neutrality can be hard to completely achieve. In this season of intens...

5 and the integrals of the second member are taken along the arcs sM of the spirals (S£) from (2"). The proof, proceeding along the same lines as that of (6), is suppressed here. Remark. The explicit values of the elementary integrals (3) are, of course, well known; but we refrain purposely from using them, as they are not needed. It is, indeed, sufficient for our proofs to know that those inte...

This paper presents parts of a design framework for collaboratively used tangible interaction systems, focusing on the theme of Embodied Facilitation. Systems can be interpreted as spaces/structures to act and move in, facilitating some movements and hindering others. Thus they shape the ways we collaborate, induce collaboration or make us refrain from it. Tangible interaction systems provide v...

Although milky nipple discharge appears frequently in infants, bloody nipple discharge is a very rare finding. We experienced a 4-month-old, breast-fed infant who showed bilateral bloody nipple discharge with no signs of infection, engorgement, or hypertrophy. The infant's hormonal examination and coagulation tests were normal, and an ultrasound examination revealed mammary duct ectasia. The sy...

Despite substantial investments in health information technology (HIT), the nation's goals of reducing cost and improving outcomes through HIT remain elusive. This period of transition, with new Office of National Coordinator for HIT leadership, upcoming Meaningful Use Stage III definitions, and increasing congressional oversight, is opportune to consider needed course corrections in HIT strate...

We present a product representation of belief spaces for planning under partial observability. In earlier work we investigated backward plan construction based on a combination operation for belief states. The main problem in explicit construction of belief states is their high number. To remedy this problem, we refrain from representing individual belief states explicitly, and instead represen...