Spontaneous abortion is the most common complication of pregnancy. Several lines of evidence indicate that immunologic effector cells may play a role in the pathogenesis of idiopathic repetitive abortions. Leukocytes form a substantial proportion of stromal cells in decidua and the endometrial granulated lymphocytes (eGL) is the predominant decidual leukocyte population in the first trimester o...

In the world, a round 40 million abortions take place every year. The corresponding figure in India is 6 million per year (Rui, 1972). T h e termination of pregnancy under modern conditions is not without psychological morbidity. T h e various types of psychological reactions which have been reported in these patients include the presence of feeling of guilt, emotional instability, a changed at...

PURPOSE To investigate the association of the HLA-A, -B and -DRB1 alleles with the occurrence of Recurrent Spontaneous Abortion. METHODS A case-control study of 200 women aged 18 to 35 years, consisting of a convenience sample of 100 women who had idiopathic recurrent spontaneous abortion and 100 women without abortion and with two or more children. Peripheral blood genomic DNA was extracted ...

BACKGROUND Approximately 205 million pregnancies occur each year in the worldwide. On the other hand, Spontaneous abortion has been reported in 15-20% of all diagnosed pregnancies. The most common cause of spontaneous abortion is chromosomal abnormalities of the embryo. Robertsonian translocation carriers specially 21-14 are the most common balanced rearrangement among the carrier couples with ...

Cytotrophoblast cells from the placenta invade the maternal spiral arteries during normal pregnancy. This results in a striking increase in luminal diameter and causes the vessels to lose their smooth muscle enabling the expansion of vascular capacity necessary to support fetal growth. Preeclampsia, growth restriction, recurrent abortion, and preterm birth in many cases are caused by abnormal i...

The aim of this study was to evaluate the therapeutic efficacy of intravenous immunoglobulin (IVIG) in the prevention of recurrent spontaneous abortion (RSA). In a double-blind, randomized, placebo-controlled study, 41 women with a history of unexplained recurrent spontaneous abortion were treated with IVIG or saline infusions during pregnancy. The birth of a child was considered a successful o...

Massive chronic intervillositis (MCI) is an unusual placental lesion associated with poor fetal growth and adverse pregnancy outcome; it has not previously been associated with spontaneous abortion or recurrent pregnancy loss. This article reports a patient who had 10 spontaneous abortions with repetitious massive chronic intervillositis documented in four of five gestations spanning all three ...

The aim of this study to evaluate the expression Programmed cell death-1 (PD-1), TGF- ß, and IL-10 in placental tissue aborted women correlation with Toxoplasma.gondii (T. gondii) these cytokines each other toxoplasmosis, during an abortion. samples have been processed used for immunohistochemistry PDL-1, IL-10, TGF-β. There was increase TGF-β, infected T.gondii, results showed that residence p...

The prognosis of couples with recurrent miscarriage is controversial despite efforts made during this century to learn about the physiopathology and treatment of this troublesome condition. Here we present our experiences of employing oocyte donation in eight couples in whom the woman was a low responder to gonadotrophin stimulation and had a previous history of recurrent abortion with negative...