BACKGROUND Fever is the most common complaint in pediatric medicine and its treatment is recommended in some situations. Paracetamol is the most common antipyretic drug, which has serious side effects such as toxicity along with its positive effects. Diclofenac is one of the strongest non-steroidal anti-inflammatory (NSAID) drugs, which has received little attention as an antipyretic drug. OB...

Objectives: The objectives of this study are to evaluate the efficacy midazolam as a means conscious sedation in pediatric odontology through three routes administration: oral, rectal and nasal administration, compare these different assess general safety Midazolam. Materials Methods: Thirty healthy non-cooperating (ASAI) patients (levels 1 2 on FRANKL scale), aged 5 years requiring minimum den...

Rationale: Rectal diazepam (0.5 mg/kg-maximum single dose 20 mg) is our standard practice for terminating prolonged (seizure > 5 minutes and continuing) or acute repetitive seizures in children, both inpatient and at home. Recently, clinically significant respiratory depression, requiring mechanical support has been reported in 8.8% of children receiving rectal diazepam (Norris et al, Dev. Med....

• EXCEDE (ceftiofur crystalline free acid) Sterile Suspension controlled bovine respiratory disease (BRD) for up to nine days after administration in a challenge model. • EXCEDE was superior to Micotil (tilmicosin) 300 Injection for lung lesion scores, respiratory scores, and rectal temperature. • Concentrations of ceftiofur and related metabolites were above the efficacy threshold for BRD path...

the methanol extract of ichnocarpus frutescens r.br. root (meif) was evaluated for its anti-pyretic potential on normal body temperature and yeast-induced pyrexia in albino rats. yeast suspension (10 ml/kg body wt.) increased rectal temperature 19 h after subcutaneous injection. the meif, at doses of 100, 200, and 300 mg/kg body wt., p.o., produced significant reduction in normal body temperatu...

The effects of E. coli endotoxin 0127 B8 on oxygen consumption, temperature, and on the activity of the proton conductance pathway in brown adipose tissue (BAT) were investigated in rats and mice. In rats an increase was observed in rectal and skin temperature, whole body oxygen consumption and GDP binding in BAT. In mice only the rise in rectal and skin temperature were significantly changed b...

Plasma prednisolone levels have been measured by radioimmunoassay after oral and rectal administration to healthy volunteers and to patients with idiopathic proctocolitis. The amount of prednisolone absorbed from a 20 mg retention enema given to patients with proctocolitis was about 44% of that absorbed from the same dose orally administered. Adrenocortical response to synthetic ACTH in patient...

BACKGROUND Inflammatory bowel disease (IBD) is characterized by most common symptoms such as rectal bleeding. Lack of specific, curative treatments tempted us to evaluate the therapeutic efficacy of quercetin against acetic acid induced IBD like symptoms. METHODS Animals were randomly divided into five groups (n = 6): naive, control, sulphasalazine and quercetin, and were pretreated for three...