Spinal cord injury (SCI) is a trauma that disturbs motor, sensitive and autonomic function and directly impacts the quality of life. After physical damage, releasing of pro-inflammatory proteins and cytokines occurs and with collaboration of immune system cells, an immune response begins in the brain tissue. The result of neuroinflammation is edema, apoptosis and release of axonal growth inhibi...

repairing the damaged nerves caused by physical injury (trauma), is one of the major challenges facing modern medical sciences. evening primrose oil (epo) extraction of oenothera biennis seed that enriches with omega-6,γ-linoleic acid and linoleic acid that they have essential role in myelination and neural membrane structure. the aim of this study was to evaluate the functional recovery of sci...

Objective(s) Human umbilical cord blood (HUCB) is now considered as a valuable source for stem cell–based therapies. Previous studies showed that intravascular injection of the HUCB significantly improves neurological functional recovery in a rat model of intracerebral hemorrhage (ICH). In the present study, we hypothesize transplanted HUCB derived mononuclear cells (UC-MCs) can decrease injur...

The inverse scattering problem on half-axis, in other words, in the spherically symmetric case, consists of finding the unknown potential from a suitable class from the scattering data S. The other problem of practical interest is to find this potential from the spectral data dρ(λ). In the literature there are recovery procedures for finding the potential from the spectral or from the scatterin...

The human brain possesses a remarkable ability to adapt in response to changing anatomical (e.g., aging) or environmental modifications. This form of neuroplasticity is important at all stages of life but is critical in neurological disorders such as amblyopia and stroke. This review focuses upon our new understanding of possible mechanisms underlying functional deficits evidenced after adult-o...

Hippocrates (460-377 BC) first described stroke over 2400 years ago. Stroke is the 4 leading cause of death in Canada (3 in the USA) and the primary cause of permanent motor and cognitive disability. The majority of strokes are ischemic. The extent of cerebral dysfunction and thus the severity of stroke are based on the location, severity and duration of ischemia. Stroke management and prognosi...