Ensuring composite services reliability is a challenging problem. Indeed, due to the inherent autonomy and heterogeneity of Web services it is difficult to predict and reason about the behavior of the overall composite service. Generally, previous approaches develop, using their modeling formalisms, a set of techniques to analyze the composition model and check “correctness” properties. Althoug...

While it is well-known that TCP performance degrades significantly on experiencing packet losses, not much is known about the way in which TCP losses occur in the real-world. In this paper, we address the questions: to what extent, and in what manner, do real-world TCP connections experience packet losses? And how effectively do TCP loss detection and recovery mechanisms deal with the packet lo...

Neural stem cell transplantation has demonstrated its therapeutic potential in many neurological disorders. The long-thought prime mechanism of action was the replacement of cells lost to injury or neuro degeneration. Now, more and more evidence has provided insight into other bystander mechanisms through which these cell grafts could bring about a functional and structural restorative benefit....

Intravenous thrombolysis improves long term functional outcomes in acute ischemic stroke. A select proportion of patients treated with thrombolysis experience rapid early neurological recovery, a powerful predictor of favourable long term outcomes. There is increased interest to augment early neurological recovery by endovascular therapy or by adjuvant intravenous thrombolytics. However, incomp...

This paper compares TCP Loss Recovery mechanisms that were proposed by the IETF to overcome TCP Reno lack of ability to recover efficiently from multiple losses in a single transmission window. The TCP extensions: NewReno, SACK and Limited Transmit, are compared under different traffic scenarios.

Recently, interest in the mechanisms underlying balance recovery following stroke has grown, because insight into these mechanisms is necessary to develop effective rehabilitation strategies for different types of stroke. Studies dealing with the recovery of standing balance from stroke are, however, limited to rehabilitation inpatients with a unilateral supratentorial brain infarction or haemo...

During DNA transcription, RNA polymerases often adopt inactive backtracked states. Recovery from backtracks can occur by 1D diffusion or cleavage of backtracked RNA, but how polymerases make this choice is unknown. Here, we use single-molecule optical tweezers experiments and stochastic theory to show that the choice of a backtrack recovery mechanism is determined by a kinetic competition betwe...

The "language network" is remarkably stable across language tasks but changes in response to injury to specific components or in response to "disconnection" of input to one component. We investigated network changes during language recovery, hypothesizing that language recovery takes place through distinct mechanisms: (a) reperfusion; (b) recovery from diaschisis; (c) recovery from structural d...

Many studies in human and animal models have shown that neural plasticity compensates for the loss of motor function after stroke. However, neural plasticity concerning compensatory movement, activated ipsilateral motor projections and competitive interaction after stroke contributes to maladaptive plasticity, which negatively affects motor recovery. Compensatory movement on the less-affected s...