introduction: lasers, light emitting diodes (leds) and super luminous diodes (slds) are widely used to treat selected musculoskeletal, integumentary and neurological conditions. the mechanisms underlying the reported treatment effects of light therapy are unclear and the physiologic effect of light on a variety of tissues, particularly neurological, is mostly unknown. a few researchers have rep...

Previously we have shown that a single subcarcinogenic dose of ionizing radiation followed by 60 wk of 12-O-tetradecanoylphorbol-13-acetate (TPA) leads to the formation of squamous cell carcinoma in Sencar mice. Our previous results also indicate that TPA pretreatment prior to irradiation results in an overall increase in total tumor incidence, including both epidermal and nonepidermal tumors (...

PURPOSE HDR (60)Co system has recently been developed and utilized for brachytherapy in many countries outside of the U.S. as an alternative to (192)Ir. In addition, the AccuBoost(®) technique has been demonstrated to be a successful non-invasive image-guided breast brachytherapy treatment option. The goal of this project is to evaluate the possibility of utilizing the BEBIG HDR (60)Co system f...

Previously we have shown that a single subcarcinogenic dose of ionizing radiation followed by 60 wk of 12-0-tetradecanoylphorbol-13-acetate (TPA) leads to the formation of squamous cell carcinoma in Sencar mice. Our previous results also indicate that TPA pretreatment prior to irra diation results in an overall increase in total tumor incidence, including both epidermal and nonepidermal tumors ...

This trial was conducted to explore the safety of recombinant fusion protein ESAT6-CFP10 as a skin test reagent for the diagnosis of Mycobacterium tuberculosis infection. Twenty-four healthy adult volunteers were recruited and randomized into four groups (groups A to D) to study four increasing doses of ESAT6-CFP10. All subjects in each dose group received an intradermal injection of reagent (0...

background: coronary angiography is a commonly performed diagnostic procedure with life saving benefits for the patient. however, this procedure involves relatively high radiation dose. the purpose of this study was to determine the average effective dose of patients undergoing coronary angiography and to estimate the associated radiation risk in terms of fatal malignancy. materials and methods...

The current study aimed to investigate the rejection and survival time of grafted skin, and the changes of Treg cells, interleukin 10 (IL-10) and transforming growth factor-β (TGF-β) in peripheral blood following skin transplantation with recombinant human interleukin-10 (rhIL-10) or cyclosporin A (CsA), as well as the role of IL-10 in immunological rejection mechanisms. A total of 36 rabbits w...

BACKGROUND/AIMS Psoriasis is a common inflammatory skin disease of undetermined etiology and poor prognosis. The current therapies have focused on direct inhibition of local inflammation, e.g. through hormone treatments. However, neovascularization plays a critical role in the development of psoriasis but so far no therapies have been developed to suppress psoriasis-associated neovascularizatio...

Background: Phototherapy is an important modality in dermatology and the number of skin diseases which can be controlled with it is increasing. In order to start treatment, the first dose of phototherapy is determined by measurement of minimal erythema dose (MED) in each patients individually or according to patient’s skin type. Objective: To determine the relationship of skin type with MED in ...