beta-lactams are a group of antibiotics with a broad spectrum of both gram-negative and gram-positive coverage. the goal of this study is to evaluate the results from studies regarding ig-e mediated hypersensitivity to penicillin and cross-reactivity with other beta-lactams. review was conducted of both retrospective and prospective studies by searching in pubmed and medline for the original an...

Autoantibodies to nuclear and smooth muscle are common in hepatitis B virus (HBV) infection. To understand their origin, we scanned protein databases and found that HBV-DNA polymerase (HBV-pol) shares 7-9 amino acid sequences with nuclear (MHC II trans-activator, nuclear pore core protein, nuclear mitotic apparatus, and polymyositis sclerosis Ag) and smooth muscle proteins (caldesmon and myosin...

McCormick and Day (1963) reported that rheumatoid factors and 7S ANF co-existing in the same seramayform high molecular weight complexes, and absorption studies have brought forward evidence of an interaction between ANF and rheumatoid factors when present in the same serum (Holborow and Johnson, 1965). However, ANF in rheumatoid arthritis have mostly been found in low frequency and chiefly in ...

A recent benchmarking effort, under the auspices of Organization for Economic Cooperation and Development (OECD) Nuclear Energy Agency (NEA), has been made to evaluate current state modeling simulation tools available model fluoride salt-cooled high temperature reactors (FHRs). The FHR effort considered in this work consists several cases evaluating neutronic parameters a 2D prismatic fuel asse...

Testosterone (T) concentrations change rapidly in the context of human competition, and these changes in neuroendocrine function may serve to modulate future aggressive behavior. However, an increase in T during competition does not translate into aggressive behavior among all individuals. Here, we examined the extent to which individual differences in trait anxiety moderate the relationship be...

Reported is the case of a 17-year-old girl with a multicystic tumor in the middle of the right kidney. Partial nephrectomy revealed an epithelial neoplasm with multilocular cystic renal cell carcinoma pattern. The cells exhibited strong nuclear reactivity for TFE3 protein and supported the diagnosis of Xp11 translocation carcinoma of the kidney. A similar case has not been found in the literatu...

The photochemical reactivity of osmocene in a biphasic water-organic solvent system has been investigated to probe its water splitting properties. The photoreduction of aqueous protons to hydrogen under anaerobic conditions induced by osmocene dissolved in 1,2-dichloroethane and the subsequent water splitting by the osmocenium metal-metal dimer formed during H(2) production were studied by elec...

Ki67 immunohistochemistry is a widely used marker of the tumor proliferative fraction. Apart from the nuclear staining of dividing cells, MIB-1 monoclonal antibody was also found to stain the cell membrane of some tumor types. Indeed, such membrane reactivity was proposed as a diagnostic feature of hyalinizing trabecular tumor (HTT) of the thyroid. To verify the diagnostic role of Ki67 membrane...

The natural-abundance carbon-13 nuclear magnetic resonance spectra of the naturally occuring pyrimidine and purine nucleosides have been determined and completely analyzed. The carbon-13 chemical shifts obtained provide information on the electronic structure and qualitatively at least correlate well with the known chemical reactivity of these molecules. The carbon-13 shifts are in general far ...

Hydroxylation Structure and Proton Transfer Reactivity at the Zinc Oxide Water Interface David Raymand, Adri C.T. van Duin, William A. Goddard, III, Kersti Hermansson, and Daniel Spångberg* Materials Chemistry, The Ångstr€om Laboratory, Uppsala University, Box 538, S-751 21 Uppsala, Sweden Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, Penn...