Journal:
:medical journal of islamic republic of iran
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maryam payan biopharmaceutics and pharmacokinetics division, department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)
nader tajik immunology research center (irc), iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)سازمان های دیگر: immunology research center (irc),
mohammad reza rouini biopharmaceutics and pharmacokinetics division, department of pharmaceutics, faculty of pharmacy, tehran university of med-ical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه تهران (tehran university)
mohammad hossein ghahremani department of pharmacology and toxicology, faculty of pharmacy, tehran university of medical sciences, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)
background: cytochrome p450 2c19 (cyp2c19) is important in metabolism of wide range of drugs. cyp2c19*17 is a novel variant allele which increases gene transcription and therefore results in ultra-rapid metabolizer phenotype (urm). distribution of this variant allele has not been well studied worldwide. the aim of present study was to investigate allele and genotype frequencies of cyp2c19*17 in...