Future coastal flood risk will be strongly influenced by sea-level rise (SLR) and changes in the frequency and intensity of tropical cyclones. These two factors are generally considered independently. Here, we assess twenty-first century changes in the coastal hazard for the US East Coast using a flood index (FI) that accounts for changes in flood duration and magnitude driven by SLR and change...

The major objective in arch surgery is to supply the basic metabolic eeds of the brain during the anastomosis. Many advances have een introduced into aortic arch surgery since Griepp et al1 used he DHCA technique. Svensson et al2 reported the safe DHCA eriod as 40 minutes. However, Ergin et al3 reported this duration s 30 minutes. The safe DHCA period also was reported to be 30 inutes under 15 ...

This study aimed to estimate genetic correlation between carcass grading and retail productivity traits and to estimate the correlated response on retail productivity traits through selection for carcass grading traits in order to assess the efficacy of indirect selection. Genetic parameters were estimated with the data from 4240 Hanwoo steers using mixed models, and phenotypes included carcass...

Here we show that blocking the adhesive function of alphavbeta3 integrin with soluble RGD ligands, such as osteopontin or cilengitide, promoted association of Rab-coupling protein (RCP) with alpha5beta1 integrin and drove RCP-dependent recycling of alpha5beta1 to the plasma membrane and its mobilization to dynamic ruffling protrusions at the cell front. These RCP-driven changes in alpha5beta1 t...

Projections of ice-sheet mass balance require regional ocean warming projections derived from atmosphere-ocean general circulation models (AOGCMs). However, the coarse resolution of AOGCMs: (1) may lead to systematic or AOGCM-specific biases and (2) makes it difficult to identify relevant water masses. Here, we employ a large-scale metric of Antarctic Shelf Bottom Water (ASBW) to investigate ci...

This study describes a simple parameterization to estimate regionally averaged changes in surface ozone due to past or future changes in anthropogenic precursor emissions based on results from 14 global chemistry transport models. The method successfully reproduces the results of full simulations with these models. For a given emission scenario it provides the ensemble mean surface ozone change...

A collection of spherical particles can be packed tightly together into an amorphous packing known as "random close packing" (RCP). This structure is of interest as a model for the arrangement of molecules in simple liquids and glasses, as well as the arrangement of particles in sand piles. We use confocal microscopy to study the arrangement of colloidal particles in an experimentally realized ...

Coat protein (CP) gene of sugarcane streak mosaic virus-AP isolate (SCSMV-AP) was expressed in E. coli and recombinant CP (SCSMV-AP rCP) was purified by linear sucrose density gradient centrifugation. Observation of purified SCSMV-AP rCP under electron microscope revealed the presence of potyvirus-like particles (PVLPs). The assembled particles were shown to encapsidate CP gene transcripts by s...

Integrins play an important part in axon growth, but integrin traffic in neurons is poorly understood. Expression of the tenascin-C-binding integrin alpha9 promotes axon regeneration. We have therefore studied the mechanism by which alpha9 integrin and its partner beta1 are trafficked along axons and at the growth cone using adult DRG neurons and PC12 cells. We have focused on the small GTPase ...