This paper describes a new design for direct sliding mode method with a high switching frequency using the PD-PI type sliding surface applied to a negative output Luo converter worked in continuous current mode for applications required constant power source such as aerospace applications, medical equipment and etc. Because of the output power and line changes, the converter model is also nonli...

This paper introduces a bi-directional DC-DC converter with adaptive fuzzy logic controller (AFLC). Bi-directional power flow is obtained by the same power components and provides a simple, efficient, and galvanically isolated converter. In the presence of DC mains, the converter operates as buck converter, powers the down stream converter, and also charges the battery. When the DC mains fails,...

The fly back converter has been widely used for multi outputs due to the simple structure and low cost in low-power applications. This paper presents a new multi output converter. It consists of a half-bridge inverter with boost converter in primary side and a fly back rectifier that is integrated with an auxiliary buck converter in secondary side. The boost converter is used to generate high v...

Scanty information exists pertaining to the length-weight relationship (LWR) and length-length relationship (LLR) parameters of longsnouted catfish, Plicofollis argyropleuron in lotic systems throughout the northern part of Peninsular Malaysia. It is vital to reveal these biological properties of P. argyropleuron in Kuala Muda and Merbok estuary for future management and to increase knowledge a...

In this study, we investigate the three-body recombination (TBR) rates on both sides of interspecies $d$-wave Feshbach resonance in $^{85}\mathrm{Rb}$ -$^{87}\mathrm{Rb}\ensuremath{-}^{87}\mathrm{Rb}$ system using $R$-matrix propagation method hyperspherical coordinate frame. Our calculations are based Lennard-Jones model potential for Rb-Rb interaction. Two different mechanisms recombination-r...

BACKGROUND Improved outcomes for severe sepsis and septic shock have been consistently observed with implementation of early best practice intervention strategies or the 6-hour resuscitation bundle (RB) in single-center studies. This multicenter study examines the in-hospital mortality effect of GENeralized Early Sepsis Intervention Strategies (GENESIS) when utilized in community and tertiary c...

The tumor suppressor retinoblastoma protein (Rb) plays a pivotal role in the regulation of cell proliferation and sensitivity to apoptosis through binding to E2F transcription factors. Loss of Rb in response to genotoxic stress or inflammatory cytokines can enhance cell death, in part, by eliminating Rb-mediated repression of proapoptotic gene transcription. Here we show that calpain cleavage o...

The product of the retinoblastoma tumor suppressor gene (Rb) can control cell proliferation and promote differentiation. Murine embryos nullizygous for Rb die midgestation with defects in cell cycle regulation, control of apoptosis, and terminal differentiation of several tissues, including skeletal muscle, nervous system, and lens. Previous cell culture-based experiments have suggested that th...

The retinoblastoma tumor suppressor protein (RB), a critical mediator of cell cycle progression, is functionally inactivated in the majority of human cancers, including prostatic adenocarcinoma. The importance of RB tumor suppressor function in this disease is evident because 25% to 50% of prostatic adenocarcinomas harbor aberrations in RB pathway. However, no previous studies challenged the co...