While 4D models (3D plus time) are becoming more prevalent in design and construction, the characteristics and use of these tools is still being explored. Research at CIFE(Center for Integrated Facility Engineering) is focusing on the usability of the models not only in terms of their visual and communicative impact but impact on the construction design process. We are developing a 4D-CAD tool ...

Background: The diagnosis of herpes simplex virus may requirevirological confirmation. Tzanck smear is an old, rapid, costeffective but nonspecific method that has been recently re-evaluatedas a method for the diagnosis of herpes virus infection. This studywas conducted to compare Tzanck smear and viral culture in thediagnosis of herpes simplex virus infection in patients clinicallysuspected to...

colloid cysts are mucous-filled masses with an outer fibrous layer. these cysts are rare developmental malformation and not a true neoplasm. they usually found incidentally and are asymptomatic; but in some cases may associate with rapid neurologic deterioration, herniation, and sudden death. recognition of this rare but important diagnosis may result in decreasing mortality. in this report, we...

A rapid, accurate tuberculosis diagnostic tool that is compatible with the needs of tuberculosis-endemic settings is a long-sought goal. An immunofluorescence microtip sensor is described that detects Mycobacterium tuberculosis complex cells in sputum in 25 minutes. Concentration mechanisms based on flow circulation and electric field are combined at different scales to concentrate target bacte...

Rapid manufacturing is emerging as a technology that enables the fabrication of three-dimensional heterogeneous objects. Compared to homogeneous objects, the fabrication of heterogeneous objects is very complicated for the processing of material information especially Functionally Graded Materials (FGMs). To take full advantage of rapid manufacturing, some methods to design and fabricate hetero...

The use of cardiac biomarkers in the intensive care setting is gaining increasing popularity. There are several reasons for this increase: there is now the facility for point-of-care biomarker measurement providing a rapid diagnosis; biomarkers can be used as prognostic tools; biomarkers can be used to guide therapy; and, compared with other methods such as echocardiography, the assays are easi...

The acute coronary syndrome is one of the most common causes of death in the industrialized countries. Since with every minute that passes, more heart muscle tissue is irreversibly damaged, it requires a rapid diagnosis and therapy. Every physician must, therefore, recognize the symptoms and immediately respond in an adequate fashion. Reading this article will prepare you to recognize the sympt...

A novel fiber-optic-based method for simultaneous time- and wavelength-resolved fluorescence spectroscopy for the rapid diagnosis of diseased tissue is demonstrated. By combining multiple bandpass and dichroic filters (405/40, 460/50, and 550/50) with different lengths of optical fiber (1, 10, and 19 m) acting as an optical delay this system enables the near real-time acquisition and characteri...

BACKGROUND Chromobacterium violaceum is a proteobacterium found in soil and water in tropical regions. The organism rarely causes infection in humans, yet can cause a severe systemic infection by entering the bloodstream via an open wound. CASE PRESENTATION We recently identified a case of severe bacteremia caused by Chromobacterium violaceum at the Hospital for Tropical Diseases (HTD) in Ho ...