نتایج جستجو برای: radiosynthesis
تعداد نتایج: 363 فیلتر نتایج به سال:
UNLABELLED 2-((1E,3E)-4-(6-((11)C-methylamino)pyridin-3-yl)buta-1,3-dienyl)benzo[d]thiazol-6-ol ((11)C-PBB3) is a clinically useful PET probe that we developed for in vivo imaging of tau pathology in the human brain. To ensure the availability of this probe among multiple PET facilities, in the present study we established protocols for the radiosynthesis and quality control of (11)C-PBB3 and f...
BACKGROUND The folate receptor (FR) is a well-established target for tumor imaging and therapy. To date, only a few 18 F-folate conjugates via 18 F-prosthetic group labeling for positron emission tomography (PET) imaging have been developed. To some extent, they all lack the optimal balance between efficient radiochemistry and favorable in vivo characteristics. METHODS A new clickable olate p...
Abstract Background The stability of precursors and reagents is utmost importance for developing a robust radiolabelling method that provides high constant radiochemical yield purity. While performing the QC [ 68 Ga]Ga-PSMA-11 injectable solutions according to Ph. Eur. Monograph has recently been published, trend instability standard PSMA-11, same used as precursor radiosynthesis, observed. Thi...
Background: The folate receptor (FR) is a well-established target for tumor imaging and therapy. To date, only a few 18 F-folate conjugates via 18 F-prosthetic group labeling for positron emission tomography (PET) imaging have been developed. To some extent, they all lack the optimal balance between efficient radiochemistry and favorable in vivo characteristics. Methods: A new clickable olate p...
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