OBJECTIVES Approximately 8000 patients with trigeminal neuralgia undergo surgery each year in the United States at an estimated cost exceeding $100 million. We compared 3 commonly performed surgeries (microvascular decompression, glycerol rhizotomy, and stereotactic radiosurgery) to evaluate the relative cost-effectiveness of these operations for patients with idiopathic trigeminal neuralgia. ...

AIMS AND BACKGROUND Few clinical data exist concerning normal brain tissue tolerance to re-irradiation. The present study evaluated long-term outcome of 22 recurrent glioblastoma patients re-irradiated with radiosurgery or fractionated stereotactic radiotherapy. METHODS Twenty-two patients were treated with radiosurgery (13, 59%) or fractionated stereotactic radiotherapy (9, 41%) for 24 lesio...

introduction: skull base meningiomas constitute a large proportion of the meningiomas, which are the most common benign brain tumors. the treatment of skull base meningiomas is specially challenging and controversial due to the proximity of these tumors to the vital brain structures. radiosurgery is now emerging as an efficient alternative treatment modality which involves the ablation of tumor...

Stereotactic radiosurgery is an emerging treatment option offered to patients with glioblastoma (GB). Radiosurgery is performed as an outpatient procedure and provides a safe and effective non-invasive treatment for focal GB. High-energy beams originating from cobalt sources placed into a helmet-shaped device (Gamma Knife®, Elekta) or generated by a linear accelerator (LINAC), rotating on a gan...

The role of stereotactic radiosurgery in the management of recurrent and newly diagnosed brain metastases was evaluated prospectively. From December 1988 to March 1991, 58 lesions in 40 patients were treated with accelerator-based stereotactic radiosurgery. All patients were followed for a minimum of 6 months or to death. The primary purpose was to determine the impact of radiosurgery on local ...

Treatment of recurrent glioblastoma is still challenging. Stereotactic radiosurgery has been accepted as a treatment option for recurrent glioblastoma after standard chemotherapy and irradiation. However, the efficacy of stereotactic radiosurgery at recurrence has been limited, mainly due to the highly infiltrative nature of the tumor which makes the lesion difficult to define as the target. To...

OBJECTIVE To investigate the effect of radiosurgery for symptomatic epilepsy associated with cerebral arteriovenous malformations (AVMs). METHODS Thirty five patients with unruptured epileptogenic AVMs were studied with a mean follow up of 43.0 months. The duration of epilepsy before radiosurgery ranged from 2 months to 21 years (mean 2.8 years). Fifteen patients showed partial seizures; eigh...

BACKGROUND Metastatic tumor in the spinal column is common, causing symptomatic spinal cord compression in approximately 25,000 patients annually. Although surgical treatment of spinal metastases has become safer, less invasive, and more efficacious in recent years, there remains a subset of patients for whom other treatment modalities are needed. Stereotactic radiosurgery, which has long been ...

BACKGROUND AND PURPOSE The purpose of radiosurgery of bAVMs is complete angiographic obliteration of its nidus. We assessed the diagnostic accuracy of 1.5T T2-weighted MR imaging and TOF-MRA images for detecting nidus obliteration after radiosurgery. MATERIALS AND METHODS The pre- and postradiosurgery MR images and DSA images from 120 patients who were radiosurgically treated for a bAVM were ...

Arteriovenous malformations (AVMs) are congenital anomalies of the cerebrovasculature with poorly formed blood vessels that shunt blood directly from the arterial circulation to the venous system bypassing the capillary network. The high pressures and flow rates in AVM vessels combined with poor construction of the abnormal shunting vessel walls make them prone to rupture and intracranial hemor...