Whole-body metastatic sun•ey scans are performed in order to determine the extent of metastases, the quality of tumor uptake, and whether the patient will benefit from therapeutic doses of radioiodine. Periodic whole-body scans also help to evaluate the success of radioiodine therapy or the necessity to repeat therapeutic treatments. Using a dual-probe rectilinear scanner and supplementing with...

A 3 year old child with Graves' disease and mitral valve prolapse became neutropenic on carbimazole therapy. She was switched to propylthiouracil but the neutropenia recurred. She was treated with radioiodine but required two doses of 113 MBq and then 198 MBq five months later before becoming hypothyroid. The mitral valve prolapse resolved when she was euthyroid on thyroxine replacement. Antith...

OBJECTIVE Non-thyroidal complication of high-dose radioiodine therapy for thyroid carcinoma might cause salivary and lacrimal gland dysfunction, which may be transient or permanent in a dose-dependent manner. However, radiation retinopathy complicating 131I therapy, has not been previously well characterized. The aim of this study was to evaluate the extent of retinal damage among patients who ...

Post-treatment or diagnostic whole-body radioiodine scintigraphy is widely used to assess the residual, recurrence, or metastases of differentiated thyroid carcinoma because of the high sensitivity and accuracy that this assessment provides. While bearing in mind all the diagnostic potential of this test, we have to consider its’ potential pitfalls, as well. Herein, we present 4 patients with d...

OBJECTIVES/HYPOTHESIS The purpose of this study is to review our experience with sialendoscopy for the management of radioiodine-induced sialadenitis. METHODS Retrospective chart review of all patients with radioiodine-induced sialadenitis treated with interventional sialendoscopy. RESULTS Twelve female patients with a mean age of 46.5 years (range, 25-77 years) underwent interventional sia...

BACKGROUND AND AIM Atherosclerosis evolves or accelerates when arteries are exposed to ionizing radiation, both early and late after exposure. Radioiodine therapy of benign thyroid disease exposes the carotid arteries to 4-50 Gy, and may thereby increase the risk of atherosclerosis. Increased risk of cerebrovascular events has been reported after radioiodine therapy. This study aimed to examine...

Selective iodide uptake and prolonged iodine retention in the thyroid is the basis for targeted radioiodine therapy for thyroid cancer patients; however, salivary gland dysfunction is the most frequent nonthyroidal complications. In this study, we have used noninvasive single photon emission computed tomography functional imaging to quantify the temporal dynamics of thyroidal and salivary radio...

Since 1942, therapy with radioiodine (RIT) has gained a major role in the treatment of benign thyroid disorders, notably hyperthyroidism caused by Graves' disease or toxic multinodular goitre (thyroid autonomy). In iodine deficient areas thyroid autonomy accounts for 40-50% of all cases with hyperthyroidism. RIT has become a cost-effective first-line procedure in autonomy-patients with latent o...

The training requirements for the supervision and administration of therapeutic procedures using radiopharmaceuticals are not defined uniformly in the Accreditation Council of Graduate Medical Education (ACGME) program requirements for different specialties. The training requirements of the Nuclear Regulatory Commission (NRC) are intended for the safe handling of radioisotopes, which is only a ...